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Details
Posted: 23-May-26
Location: New Brunswick, New Jersey
Categories:
Healthcare
Staff/Administrative
Internal Number: 275367
Position Summary:
Rutgers, The State University of New Jersey, is seeking a Postdoctoral Associate in the Department of Microbiology, Biochemistry and Molecular Genetics within the New Jersey Medical School (NJMS).
Under the direction of the Principal Investigator the Post doctoral Associate will perform research. The Altindis Lab studies viral insulin/IGF‑1‑like peptides (VILPs) – sequences encoded by viruses that mimic human insulin and IGF‑1. We investigate how VILPs interact with and inhibit the human IGF‑1 receptor (IGF1R) with high specificity, without affecting the insulin receptor. Using structural biology (cryoEM), proximity labeling (TurboID), phosphoproteomics, and mouse models (including bGHTg acromegaly mice and breast cancer xenografts), we aim to uncover fundamental mechanisms of IGF1R antagonism and develop peptide‑based inhibitors for diseases such as cancer and diabetic complications.
Among the key duties of this position are the following:
Under the direction of the Principal Investigator the Post doctoral Associate will perform research. The Altindis Lab studies viral insulin/IGF‑1‑like peptides (VILPs) – sequences encoded by viruses that mimic human insulin and IGF‑1. We investigate how VILPs interact with and inhibit the human IGF‑1 receptor (IGF1R) with high specificity, without affecting the insulin receptor. Using structural biology (cryoEM), proximity labeling (TurboID), phosphoproteomics, and mouse models (including bGHTg acromegaly mice and breast cancer xenografts), we aim to uncover fundamental mechanisms of IGF1R antagonism and develop peptide‑based inhibitors for diseases such as cancer and diabetic complications.
Among the key duties of this position are the following:
- Performs independent research involving cell culture, receptor signaling assays, in vivo mouse models, and molecular biology techniques under the PI's guidance.
- Meets with the principal investigator to establish goals and objectives for VILP-related projects
- Communicates regularly with the P.I.
- Maintains detailed and accurate experimental records.
- Supervises and trains subordinate staff.
- Reads current scientific and technical literature relevant to the laboratory's mission.
Minimum Education and Experience:
- Ph.D. in Molecular Biology, Biochemistry, Cell Biology, or a closely related field.
City: Newark
State: NJ
Physical Demands and Work Environment:
PHYSICAL DEMANDS:
- Standing, sitting, walking, talking, or hearing. No special vision requirements.
- Must be able to lift or exert force up to ten (10) pounds.
- Able to work with mice.
WORK ENVIRONMENT:
- Laboratory/Animal Care Facility/Office environment.
- Moderate noise.
Posting Number: 26ST1116
About Rutgers University
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.
More Jobs from This Employer
https://main.hercjobs.org/jobs/22297932/postdoctoral-associate
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