School: Harvard Medical School

Position Description:

• Provide expert consultation and training to faculty, postdoctoral fellows, and graduate students on experimental design, sample preparation, acquisition strategies, quantitative imaging, data validation, and image analysis
• Advise on imaging approaches across a wide range of biological and biomedical applications and specimen types, from single molecules to whole organisms
• Stay current with advances in imaging and image analysis, and apply this knowledge to consultations and training offered by the core
• Offer ongoing support to trained core users, including guidance as experiments evolve, troubleshooting, and interpretation of imaging data
• Work to enhance rigor, reproducibility, and best practices in imaging experiments performed in the core
• Support grant applications by advising on experimental design and providing expert letters of support

• Design and deliver workshops on light microscopy theory, modern and emerging quantitative imaging techniques, and image analysis best practice for trainees and research scientists
• Develop and contribute lectures and laboratory modules to HMS graduate programs
• Create educational resources that promote technical rigor and experimental best practices in imaging experiments
• Stay current with advances in imaging and image analysis, and translate relevant new methods into educational offerings for the local research community

• Direct operation and strategic development of a 16-instrument light microscopy facility, including widefield fluorescence, spinning disk confocal, laser scanning confocal, total internal reflection fluorescence (TIRF), light sheet (diSPIM & lattice) and 3D structured illumination microscopy (SIM) systems
• Evaluate and implement new technologies and instruments in the core, to maintain cutting-edge capabilities
• Oversee maintenance and optimization of both commercial and custom-built imaging platforms
• Serve as primary liaison with external microscope vendors to oversee system installation, performance optimization, maintenance, and technical issue resolution

• Recruit, supervise, and mentor core facility staff

• Ensure compliance with institutional and environmental health and safety regulations
• Manage facility operations, budgeting, financial planning, and reporting
• Oversee scheduling, billing, and user access systems

• Lead preparation of shared instrumentation and equipment grant proposals
• Contribute to long-term planning for core growth and scientific impact

Basic Qualifications:

• PhD in biology, physics, or a related discipline
• Minimum 10 years of experience performing light microscopy experiments
• Minimum 10 years of experience in advanced microscopy systems including widefield fluorescence, spinning disk confocal, laser scanning confocal, TIRF, structured illumination microscopy, and light sheet microscopy
• Minimum 5 years of experience working with custom-built systems imaging systems.
• Minimum 10 years of experience with commercial and open-source image acquisition and analysis software
• Core facility or shared instrumentation environments
• Demonstrated experience with quantitative microscopy applications including live specimen imaging, ratiometric imaging, spectral imaging, FRET, FRAP and single molecule tracking
• Expertise in NIS-Elements for acquisition and analysis, MicroManager for microscope control, FIJI for image processing, and Python for scripting and automation
• Demonstrated experience teaching light microscopy and/or image analysis to PhD-level research scientists in a formal classroom setting
• Strong leadership, organizational, and communication skills
• Experience organizing microscopy and image analysis workshops and courses.

Contact Information:

Contact Email: cbsearch@hms.harvard.edu

Equal Opportunity Employer:

Salary Range:

About Harvard University

Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.

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