The Park Lab at Boston Children's Hospital, Harvard Medical School is seeking highly motivated applicants for the position of Research Assistant in the lab. We identify and define key mechanisms whereby extracellular matrix (ECM) components regulate molecular and cellular processes that control the onset, progression, and outcome of acute and chronic inflammatory disease. For example, we found that proteoglycans inhibit innate immune responses in the lung, cornea, and liver to limit inflammatory tissue injury, but that certain pathogens exploit these fundamental functions of proteoglycans to inhibit immune clearance and promote their pathogenesis. We are interested in cell-matrix and host-pathogen interactions that shape immune responses, tissue repair processes, and matrix remodeling mechanisms. Research in the Park Lab is multidisciplinary and takes advantage of genetically modified mice, primary cell cultures, engineered cell lines, high throughput technologies, and diagnostics, and a wide range of molecular, biochemical, cellular, microbiological, glycobiological, structural, and histological
techniques.
This Research Assistant II/III will be responsible for:

• Depending on ability, leading a component of an NIH-funded research project.
• Troubleshoot procedures if experimental results are unexpected or the quality of specimens is poor. May suggest alternative routine procedures to crosscheck own findings. Performs techniques typically required for the laboratory/study.
• Assists with planning specific research procedures, and coordinating schedules of experiments and procedures. Develops and troubleshoot new techniques specific to the lab.
• Maintains accurate records of results and methodologies into a log of work performed. Compiles and helps analyze data, preparing charts, graphs, and results of studies.
• Demonstrates basic laboratory techniques to laboratory assistants and technicians, research fellows, residents, and students. Contributes to the team within and between departments and organizations.
• Ordering of reagents, maintenance of lab in general.
• Animal care (splitting, breeding, weaning).

In order to qualify, you must have:

• A Bachelor's Degree or higher in STEM.
• A minimum of one year of relevant work expereince.
• Analytical skills to resolve complex problems requiring the use of scientific, mathematical, or technical principles and in-depth, experienced-based knowledge.
• Ability to communicate effectively both orally and in writing.

Boston Children's Hospital offers competitive compensation and unmatched benefits including flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes.