General summary/purpose:

The Department of Affective Disorders is seeking a highly-motivated Sr Bioinformatician to work at the forefront of genomics research on mood disorders, including depression and bipolar disorder. The Sr Bioinformatician will serve as an integral part of a multi-disciplinary genomics research team by developing and implementing software tools, pipelines and workflows for analyzing high-throughput genomics, epigenomics, and transcriptomics data.

Duties and Responsibilities

• Develop and implement data collection quality assurance procedures to ensure validity and reliability of study results.
• Develop analysis methodology leveraging high dimensional multi-omics sequence data, including defining in detail data requirements, data sources and proper data collection procedures.
• Provide statistical advice to faculty, staff & graduate students as needed in regard to study design, sample size and power analysis, etc.
• Collaborates with investigators to develop objectives, designing sampling and data collection to achieve study results.
• Interpreting, presenting and summarizing analyses in various formats including tables, graphics, oral reports, and written reports. This includes internal presentations within the center as well as external communications to collaborators across institutions and conferences.
• Merging data, creating, and recoding variables to prepare data for analyses.
• Analyzing longitudinal, cross-sectional and clustered data using a variety of standard statistical techniques, including linear and logistic regression, mixed effects models, survival analysis, principal component analysis, and others as needed.
• Develop and apply computational and statistical methods for the integrated analysis of high throughput sequencing studies that include whole genome, whole exome, methylation, RNA sequencing, single cell and/or liquid biopsy platforms.
• Carry out data analyses in parallel on large compute cluster; integrate, organize and analyze program output.
• Manage research datasets on file servers and ensure their appropriate backup, completeness, correctness and integrity.
• Prepare reports of findings by compiling results, generating figurers, and preparing tables from analyses of genomic studies.
• Perform data analysis and interpretation; utilize knowledge of statistics and quantitative analysis.
• Assist in preparing scientific presentations, grant applications and manuscripts, with the opportunity if appropriate to present at meetings and contribute as a lead and/or co-author on manuscripts.
• Liaise with external collaborative groups independently of the PI to present research updates and facilitate research with external collaborators.
• All other responsibilities as assigned.

Special knowledge, skills, and abilities

• Ability to work independently.
• Ability to interact with faculty and staff on research teams, in clinical programs, and with educational outreach initiative to strategize about their communication needs.
• Attention to detail a must. Good proofreading skills.
• Excellent oral communication skills to deal effectively within and outside the department.
• Excellent written communications skills in a variety of forms, print material, website content, speeches, and publicity materials.
• Knowledge of and aptitude for graphic design and typography.
• Skilled in computer programs such as Microsoft Word, Outlook, PowerPoint, Excel and Publisher.
• Enthusiasm and willingness to learn about the work of the department as well to acquire new technical skills as needed.
• Excellent organizational skills to work effectively in an environment that requires balancing multiple assignments.
• Ability to interact effectively with individuals at all levels and from diverse cultures.

• Proficiency in shell scripting and/or programming language such as Python or Perl.
• Knowledge of web programming a plus.
• Strong oral and written communications skills and ability to work as part of a multi-disciplinary team.
• Ability to work independently and manage multiple projects in a dynamic environment with changing priorities.

• Master's Degree in biostatistics, epidemiology, or related quantitative field.
• Three years related experience.
• Demonstrated ability on significant graduate project or additional doctoral education may substitute for experience to the extent permitted by the JHU equivalency formula.

Master?s Degree in bioinformatics.

Doctoral Degree preferred.

Experience working in a Unix/Linux environment and managing large datasets.

Experience using analytic software such as R, SAS or Stata.

Prefer highly specialized advanced knowledge, education and/or training in a specialized field of study to conduct research.

Classified Title: Sr. Biostatistician 
Job Posting Title (Working Title): Sr Bioinformatician   
Role/Level/Range: ACRP/04/ME  
Starting Salary Range: $64,600 - $113,300 Annually ($76,800 targeted; Commensurate w/exp.) 
Employee group: Full Time 
Schedule: M-F / 8:30A-5:00P 
FLSA Status: Exempt 
Location: Remote 
Department name: SOM Psy Affect Disorders and Psych Genet  
Personnel area: School of Medicine 

About Johns Hopkins University

Johns Hopkins University remains committed to its founding principle, that education for all students should be grounded in exploration and discovery. Hopkins students are challenged not just to learn but also to advance learning itself. Critical thinking, problem solving, creativity, and entrepreneurship are all encouraged and nourished in this unique educational environment. After more than 130 years, Johns Hopkins remains a world leader in both teaching and research. Faculty members and their research colleagues at the university's Applied Physics Laboratory have each year since 1979 won Johns Hopkins more federal research and development funding than any other university. The university has nine academic divisions and campuses throughout the Baltimore-Washington area. The Krieger School of Arts and Sciences, the Whiting School of Engineering, the School of Education and the Carey Business School are based at the Homewood campus in northern Baltimore. The schools of Medicine, Public Health, and Nursing share a campus in east Baltimore with The Johns Hopkins Hospital. The Peabody Institute, a leading professional school of music, is located on Mount Vernon Place in downtown Bal...timore. The Paul H. Nitze School of Advanced International Studies is located in Washington's Dupont Circle area.

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