Researcher 1 - Masonic Institute on the Biology of Aging and Metabolism

Are you passionate about cutting-edge aging research and eager to work hands-on with groundbreaking science? Join the Masonic Institute on the Biology of Aging and Metabolism (MiBAM) in our Mouse Core, where youâ™ll play a key role in advancing discoveries that could transform human health!

In this dynamic position, you'll be at the heart of our research, managing and maintaining our mouse colony, ensuring smooth operations through our mouse cloud database, and handling everything from specimen labeling and biological sample archiving to tracking healthspan data. Youâ™ll also dive into molecular biology techniques like immunoblotting and qRT-PCR, conduct animal necropsies and tissue preservation, and even coordinate the shipment of critical biological samples.

This is more than just a jobâ”itâ™s an opportunity to contribute to cutting-edge aging science, collaborate with passionate researchers, and continuously expand your knowledge in a field thatâ™s shaping the future of medicine. If you're curious, detail-oriented, and excited to make a real impact in longevity research, weâ™d love to have you on our team! 

Essential and other Functions:

50% Laboratory Research
Assist in coordinating animal tissue dissections for efficient sample collection for experimental needs. Animal husbandry, mouse colony management, collect and record data collected on live animals, mouse necropsies, collection and preservation of biological samples, performs IVIS imaging, dosing mice for drug studies, communicates with RAR veterinary staff concerning animal health cases, facilitates animal transfers, monitors health of experimental animals.

25% Sample and Data Management
With supervised oversight, use the labâ™s unique colony management database to create animal identifiers and cage cards, prepare necropsy reports and labels for biologic samples, archive samples in the tissue bank and ship biological samples to collaborators, maintain up to date records of culling and anesthesia logs.

25% Cellular and Molecular biology
With supervised oversight, prepare tissue lysates, isolate RNA and protein, quantitate nucleic acids and protein levels, perform qRT-PCR, PCR genotyping, nucleic acid and protein electrophoresis, prepare and refresh cell culture media. Establishing and maintaining mouse embryonic fibroblasts and culture of neuronal cell lines for functional assays.

All required qualifications must be included in the application materials.

Required Qualifications:

• BS/BA in a biomedical discipline, or a combination of related education and work experience to equal 4 years.
• Experience working with mice.
• Must have strong problem-solving skills, an ability to multitask and to work independently. 

Preferred Qualifications:

• Applicants should have an interest in health sciences and interest in working with laboratory animals.
• Experience with the Mouse Cloud database used to inventory mice and biological samples.
• Knowledge about DNA damage, DNA repair and genome instability disorders

About University of Minnesota Twin Cities

The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.

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