Chicago, Illinois
Chapel Hill, North Carolina
Stanford, California
Washington, D.C.
Wilmington, North Carolina
USA - MA - Boston
Posted: 08-Jan-25
Type: Full-time
Categories:
Internal Number: R120327
A full time Researcher position is available in the laboratory of Dr. Chenran Wang in the Department of Radiation Oncology. The researcher is dedicated to studying autophagy functions in glia for breast cancer brain metastasis. The Wang laboratory also focuses on the functions and mechanisms of selective autophagy and lipid metabolisms in neural stem cells, microglia, and astrocytes.
The lab developed novel genetically engineered mouse models to study roles of autophagy genes in brain developmental and in progress of breast cancer brain metastasis. We use a variety of techniques including single cell RNA-seq, single nuclei RNA-seq, single cell lineage tracing, human iPSC derived cerebral organoids, chemogenetics, clarity technique, patch clamp, super-resolution images, metabolic/molecular/cellular approaches to gain insights in autophagys functions in human developmental disorders and breast cancer brain metastasis.
Required Experience
Master's Degree or equivalent experience required; PhD preferred.
4-5 years of relevant experience required.
5-7 years of relevant experience preferred.
At least one year of experience in neuroscience research, cell and molecular biology, or cancer biology preferred.
Additional Qualifications Considered
Experience in neural stem cell, cancer biology, signal transduction, metabolism, autophagy, glia cells, organoids, and genetic mouse models.
Experience in scRNAseq and snRNAseq is ideal.
Good oral and written communication skills.
Ability to work and collaborate effectively with students, faculty and staff from a variety of culturally diverse backgrounds.
