A Postdoctoral Research Scientist position is available for a highly motivated candidate to work on a new DOE-funded project investigating the response to low doses of radiation in bone marrow stem cells, the target cell type for radiation-induced acute myeloid leukemia (AML). The project will leverage a 3-dimensional organoid model that reproduces key elements of the bone marrow niche to support the growth and function of human blood-forming stem cells, and will compare responses in bone marrow stem cells from healthy donors and donors with clonal hematopoiesis, a defined pre-leukemic condition that may sensitize individuals to radiation-induced leukemia. Endpoints will include changes in cell-type distribution, generation of reactive oxygen species, and both bulk and single-cell RNA-Seq analyses. 

Our laboratory is in the Center for Radiological Research (crr.columbia.edu) in the Department of Radiation Oncology at Columbia University Irving Medical Center in Upper Manhattan, and the project is a collaboration with investigators in the Columbia Stem Cell Initiative (https://www.stemcell.columbia.edu). This is an outstanding opportunity to work with investigators in leading radiation biology and stem cell laboratories.

Minimum Degree Required

Ph.D. and/or M.D.

Minimum Qualifications

Candidates must have experience in molecular biology and cell culture, as well as excellent communication and writing skills. A background in stem cell biology, 3D organoids, radiation science, and/or cancer biology is also strongly preferred.

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.  The above hiring range represents the University?s good faith and reasonable estimate of the range of possible compensation at the time of posting.

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.  The above hiring range represents the University?s good faith and reasonable estimate of the range of possible compensation at the time of posting.

About Columbia University

Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.

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