We are seeking candidates for a postdoctoral position in the laboratory of Dr. Michael Weiss, Department Chairperson, in the Department of Biochemistry and Molecular Biology. The Weiss lab studies focus on Diabetes Mellitus and Peptide Hormones: Principles of receptor recognition, evolution of insulin and insulin-like signaling systems, structure- activity relationships and analogue design with application to global health; Reproductive Endocrinology: Protein-nucleic acid interactions, structural aspects of gene regulation.

Application to sex determination and intersex abnormalities of the newborn; and Applications of Structural Biology in Biochemistry and Pharmacology: Multi-dimensional NMR methods in solution with application to structures of proteins, protein-ligand complexes and nucleic acids. Crystal structures of biomolecules.

We are seeking a Post doctorate to express and purify the insulin receptor from mammalian cell culture for use in cryo-EM and other studies and to express and purify insulin and insulin analogs from yeast-based expression system. This candidate should be self-motiving and able to design and execute experiments independently or in a collaborative environment. A candidate may be involved with the training of junior laboratory personnel on these protocols and other techniques


As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana. More information about diversity and inclusion efforts at IUSM can be found at https://faculty.medicine.iu.edu/diversity.

Doctorate or terminal degree required. PhD required with relevant experience in protein expression and purification. Experience with funded for at least three years by the NIH

Dr. Joe D Racca, PhD
jracca@iu.edu