Research - Laboratory/Non-Laboratory, Staff/Administrative
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The University of Washington, Department of Laboratory Medicine and Pathology (DLMP) is a broad and dynamic department that strives for a consistent level of high achievement in all of its activities. The Department offers full diagnostic services in all areas of Laboratory Medicine and Pathology, is a top ranked research organization as measured by research awards from the National Institutes of Health and offers an array of specialized educational training programs.
UW Medicine DLMP operations are based at the University of Washington Medical Center, Harborview Medical Center, South Lake Union, Northwest Hospital and the Seattle Cancer Care Alliance. Faculty members also serve at Seattle Children's Hospital, the Veteran’s Administration Puget Sound Healthcare System, and the Fred Hutchinson Cancer Research Center. These collaborative efforts have generated innovative, translational studies in the basic mechanisms of disease.
The Rabinovitch/Sweetwyne Laboratory in the DLMP on the main campus at the University of Washington has an outstanding opportunity for a 1.0 FTE Research Scientist/Engineer 1. Working under the oversight of the principal investigator, the individual hired for this position will perform laboratory experiments, data analysis, and assist in preparing reports. This position is funded for at least 2 years with the potential for longer term support as funding permits.
The Research Scientist / Engineer 1 (RSE1) will report to, and work closely with senior co-investigators, Dr. Sweetwyne and Dr. Sanchez-Contreras. With appropriate training from lead co-investigators and an RSE2, the RSE1 will be expected to work independently on assigned tasks focusing on the cellular mechanisms of mitochondrial mutation and function in the context of aging. The RSE1 will maintain mouse colonies as well as perform primary cell/tissue isolations and prepare DNA sequencing libraries. In this position the RSE1 will assume responsibility for coordinating sample intake and preparation with outside collaborating research partners as well as collaborating with other members of the lab as needed. The RSE1 will rigorously document their research progress and present at laboratory meetings. They will also assist Drs. Sweetwyne and Sanchez-Contreras in data analyses and compilation as relevant for the project.
RESPONSIBILITIES: Specific research activities will include but will not be limited to: •Rodent work (Biological sample collection, genotyping, minor/major surgery, and husbandry) •DNA/RNA isolation and quantification •DNA sequencing library preparation •Primary cell culture (human and mouse) •Interacting with volunteers for human sample collection •Protein expression analysis by Western blotting, ELISA •MACS separation •Mitochondrial Isolation •Immunohistochemistry/immunocytochemistry •Fluorescent microscopy, image acquisition (confocal/brightfield) and analysis
REQUIREMENTS: •Bachelor’s Degree in Cell and Molecular Biology or related field with at least 1 or more years of experience in biomedical research bench work -or- equivalent combination of educational, postdoctoral and research staff experience in human/animal models of molecular and cellular biology. •Established record of independent execution of research tasks. •Proven experience with IACUC compliant mouse handling as well as micro-pipetting and basic laboratory dilution calculations. •Willingness and interest in learning new techniques.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
DESIRED EXPERIENCE Strong skills in organization and ability to clearly communicate results and issues in a timely manner. Collaborative team player. Ability and willingness to execute established protocols carefully and consistently with minimal supervision. Experience working in either next generation sequencing or tissue culture are not required but will be considered a plus.
The Rabinovitch/Sweetwyne laboratory is committed to fostering an environment that welcomes individuals from diverse backgrounds into a collaborative, supportive and rigorous scientific working group.
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.