Research Support - Laboratory/Non-Laboratory, Staff/Administrative
Duties and responsibilities:
80% Performing peptide and small molecule solid-phase organic synthesis. Performing RP-HPLC purification and analytical characterizations including analytical RP-HPLC and HR-Mass Spec analysis. Performing and interpreting pharmacological assays to characterize ligand potency, efficacy, and binding.
10% Lab Management: Ordering supplies and chemicals, book/record keeping, chemical inventory, general organization, prepare for laboratory inspections, check that all lab stock solutions and general supplies are available, organize lab parties and gatherings. Performing weekly checks of equipment as well as freezers and oversight of other equipment in the laboratory. Additional duties include library work, photocopying articles, and attending meetings as requested.
10% Assisting in the writing of technical reports and articles for publication. Keeping appropriate laboratory records, detailed record keeping with weekly updates, preparation of reports, presenting results, and working with technicians, graduate students, and postdoctoral fellows; review literature as assigned.
All required qualifications must be documented on application materials
Required qualifications: -Bachelor's degree (in Chemistry, Medicinal Chemistry, or related Organic synthesis field, preferred) and 1 year of related experience or equivalent combination of education and experience to equal five (5) years. (Undergraduate course work will have included General and Organic Chemistry with laboratory components and experience.) -Excellent verbal and written communication skills as well as computer literacy (proficiency in Microsoft Excel, Word, and PowerPoint) are essential. -Ability to work independently, reliable and self-motivated. -Ability to meet deadlines and work in a high-paced environment. -Attentiveness to details, highly organized and initiative driven, excellent organization and communication skills are essential.
Preferred qualifications: -At least 3 years of experience in a medicinal chemistry research laboratory. -Documented experience utilizing CEM Discover and LibertyBlue microwave synthesizers, as well as Advanced Chemtech Vantage and LabTech 1 synthesizers. -Documented ability to synthesize macrocyclic peptides. -Documented ability to synthesize peptides greater than 25 amino acids in length and experience using solid-phase extraction cartridges. -Documented experience utilizing Shimadzu HPLC instrumentation with LabSolutions software and Bruker BioTOFF II ESI/TOF-MS and AB-Sciex 5800 MALDI/TOF-MS systems.
Internal Number: 341948
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.