Research - Laboratory/Non-Laboratory, Staff/Administrative
Rutgers, The State University of New Jersey is seeking a Research Associate III for Pharmacology, Physiology and Neuroscience within the New Jersey Medical School. In collaboration with faculty members, the Research Associate will test the central hypothesis that opening of Cx43 hemichannels by S-nitrosylation is a required step in endothelial cells for Ca2+ entry and enhanced production of NO and EDHF, whose signaling regulates longitudinal propagation of vasodilation along the vessel length. Specifically, the Research Associate will identify the presence of connexin-43 hemichannels in endothelial cells and determine whether these hemichannels are activated by endothelium-dependent vasodilators via direct S-nitrosylation. The Research Associate will also determine the specific role of endothelium Cx43 hemichannels in Ca2+ entry and its mediation of EDHF production in endothelial cells.
Among the key duties of this position are the following:
As directed, performs various research and technical operations relative to the ongoing investigatory activities of the laboratory.
Ensures laboratory equipment is maintained and in good working order.
Assists with the instructing and training of fellows, medical students, research assistants and laboratory technicians in laboratory techniques.
Record and analyze data from experiments.
Maintains a proper data notebook pursuant to the standards of the Department and the PI.
Assists in conducting a continuous program of research and development regarding the analytical and instrumentation functions of the laboratory,
Constantly evaluating existing procedures, revising where necessary, proposing new procedures where required and evaluating suggestions and changes as proposed, in order to keep the methodology and procedures current.
Assists with the preparations of proposals, formal applications and justification for grant application.
Minimum Education and Experience:
Master's Degree in a relevant science plus one (1) year of related research experience, or a Bachelor's Degree in a relevant science plus two (2) years of related research experience.
Experience in cardiovascular biology and connexin/pannexin channels.
Expertise in electrophysiological techniques and endothelial tissue culture.
Excellent communication skills.
Individual must be able to work independently.
Required Knowledge, Skills, and Abilities:
Ph.D. and or M.D./Ph.D. with degree in Physiology or Neuroscience.
Physical Demands and Work Environment:
Laboratory environment. Moderate noise.
Posting Number: 21ST1967
Location: Newark (RBHS)
Internal Number: 137210
About Rutgers University
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.