Research - Laboratory/Non-Laboratory, Staff/Administrative
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The Department of Immunology has an outstanding opportunity for a Research Scientist 2.
Parasitic worms (helminths), allergens, and certain protists all induce a “type 2” immune response that causes increased mucus production (runny nose), smooth muscle hypercontractility (coughing & sneezing), and other changes in tissue function. Why the immune system treats all of these triggers the same way remains unclear. To address this and other questions, research in the Moltke labs focuses on the initiation and regulation of type 2 immunity. Currently, the lab focuses on specialized cells in the intestinal lining called tuft cells that detect the presence of worms in the intestine using the same proteins that taste buds use to detect food. Our findings should inform the development of improved therapies for asthma, allergy, and related disorders.
The Research Scientist 2 will help manage the day-to-day operation of the Moltke lab and perform experiments. The Research Scientist 2 will perform a variety of tasks to support research in the lab, including maintenance of a mouse colony and helminth stocks, and ordering of lab supplies. For these tasks, the Research Scientist 2 is expected to use established systems/approaches to solve well-defined problems with a limited number of variables and few complex features. The Research Scientist 2 will also perform projects of larger scope that include conducting experiments and tests in the immunology field, making measurements, and recording data. They will work under limited supervision, contribute data for use in reports and publications, and will be expected to participate in regular laboratory meetings and events. The Research Scientist 2 will also collaborate with other lab members, provide ideas to improve group efficiency, and contribute to the procurement of additional funding. The successful candidate will translate clear expectations regarding time management and task prioritization into efficient support for the research team. Lastly, the Research Scientist 2 will monitor and direct the work of junior staff for completion of routine laboratory tasks.
The Research Scientist 2 will be responsible for performing or directing the following tasks:
•Maintain a breeding colony of mice under specific-pathogen-free conditions, including animal husbandry, weaning, ear tagging, genotyping, and updating the mouse census •Basic molecular biology, including PCR, DNA preparation and cloning •Maintain laboratory stocks of worms (helminths) •Prepare laboratory reagents •Inventory, order, and restock laboratory supplies •Prepare the lab for inspections •Multicolor flow cytometry and immunofluorescence microscopy •Perform experimental procedures on mice, including bleeding and cell and tissue isolation •Organize and analyze research data •Participate in laboratory meetings •Perform related duties as required
MINIMUM REQUIREMENTS •Bachelor’s degree in biological sciences or related field •2 years of job-related experience •Excellent organizational, computational and record keeping skills, attention to detail, ability to work independently but within a team environment, and willingness to work with laboratory mice •Exceptional communication and interpersonal skills
Equivalent education and/or experience may substitute for minimum requirements.
DESIRED REQUIREMENTS •PhD in biological sciences, biochemistry, or related field •Experience with laboratory mice, molecular biology, immunology, and/or tissue culture
CONDITIONS OF EMPLOYMENT The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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