Responsible for the design of independent research studies
Collaborate across teams on multiple ongoing projects.
Regularly conduct research experiments and procedures which include but are not limited to:
Performing virus injections in specific stereotaxically located brain areas
Performing immunohistological staining and analysis using microscopy and imaging techniques
Performing in vivo fiber-photometry fluorescence recordings
Performing confocal and two-photon calcium imaging in brain slices
Performing behavioral tests in mice
Analysis and interpretation of results
Recording cell activity in vivo in behaving freely-moving mice
20% Other Scientific Duties
Review literature as suggested by the research
Select relevant facts, techniques and procedures from the literature
Present at lab meetings
Candidates will be responsible for writing manuscript drafts reporting experimental results as well as review articles.
About the lab:
The research focuses on the mechanisms and physiological consequences of the astrocyte-neuron signaling, aiming to understand its role in physiological and pathological aspects of synaptic physiology and brain function. Astrocytes, classically considered as supportive cells for neurons without a direct role in brain information processing, are emerging as relevant elements in brain physiology through their ability to regulate neuronal and synaptic activity. We are studying how astrocytes respond to neuronal activity, how they control neuronal activity and synaptic transmission and plasticity, and how they are involved in neural network function to determine animal behavior
For more information, please visit: https://www.araquelab.com/research/
PhD in in Biology or a related scientific discipline
Bachelor´s degree in Biology, Biochemistry, Biomedicine, Biochemistry Engineering or a related scientific discipline.
Work experience for at least 6 years in a neuroscience laboratory.
Microscopy and calcium imaging techniques.
In vivo fiber-photometry fluorescence recordings, analysis and interpretation.
Brain stereotaxic surgery and virus injections of virus in specific brain areas.
Test and analysis of animal behavior.
Immunohistochemistry and in situ hybridization
Classic and Gateway cloning, mRNA isolation, RT-PCR, Western blot.
Previous scientific productivity.
Internal Number: 341683
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.