UCSD Layoff from Career Appointment: Apply by 05/04/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 05/13/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Division of Host-Microbe Systems & Therapeutics brings together a diverse group of scientists and physicians for interdisciplinary research on the interactions of humans and the microbial world in both health and disease. Fundamental principles of microbiology, immunology, pharmacology, -OMICs (genomics, proteomics, metabolomics, and the human microbiome) and state-of-the-art systems biology are focused on the pathogenesis of common childhood infectious diseases and inflammatory disorders, to inspire innovative discovery programs and translational studies of new drugs and interventions to restore optimal health in childhood and throughout life.
The Laboratory Assistant will be part of a dynamic preclinical behavioral neuroscience and microbiome group studying the gut-brain axis and mechanisms underlying several behaviors that are impaired in psychiatric disorders, like anhedonia, motivational deficits, anxiety, cognitive impairment, and biodrug dependence. Under supervision, the Laboratory Assistant will be responsible for assisting with and performing routine experimental procedures and testing of laboratory rats (ex. visceral pain model, depression and anxiety models) in various behavioral tasks including, but not limited to: behavioral observation tasks such as habituation, grooming, forced swim test, social avoidance, sucrose or alcohol preference, open field test, elevated plus maze, marble burying, and prepulse inhibition.
The Laboratory Assistant will prepare and administer experimental biodrugs to rats during testing via several routes of administration, which includes oral gavaging (predominantly); and intraperitoneal, subcutaneous, and intragastric (occasionally); will perform serial blood draws; and will extract, dissect, process, and section brain and cecal tissue from rats; and collect fecal samples. The Laboratory Assistant will also be expected to assist with or perform (if competent) survival surgeries involving, but not limited to: vagotomy and implantation of intracranial recording and stimulating electrodes for electrophysiological assessments. The Laboratory Assistant will collect, manage, analyze, and present data from all laboratory testing instruments.
Responsibilities will also include general lab maintenance, including maintaining clean and safe testing areas according to IACUC and EH&S policies and regulations, maintaining testing equipment, assisting with protocol amendments and routine lab inspections, and assisting with ordering and stocking of supplies. Depending on level of independence and intellectual input, there will be opportunities for the Laboratory Assistant to present research at scientific conferences, co-author scientific publications, and receive training and guidance for a career in academic or industry research.
Graduation from high school or a GED and two (2) years of laboratory experience or two (2) years of college including courses in the natural, physical or social sciences and one (1) year of laboratory experience, or an equivalent combination of education and experience and knowledge and abilities essential to the successful performance of the duties assigned to the position.
Thorough knowledge of or experience with sterile/aseptic technique.
Proven ability to follow written and verbal protocols, techniques, and instructions. Strong organizational and troubleshooting skills, cooperative, enthusiastic and team-oriented, attention to detail and thoroughness in record keeping, ability to take initiative in maintaining and improving lab operations.
Ability to use basic laboratory equipment including centrifuges, balances, pH meters, fume hoods, and biosafety cabinets.
Knowledge of bio and chemical safety techniques and practices. Ability to follow established Safety and Biohazardous Material Guidelines and implement measures to ensure compliance and maintain associated records.
Willingness to adhere to established UCSD guidelines for safety and environmental issues.
Proficient experience with the operation of a personal computer and software applications, such as Microsoft Office (Word, Excel, Access), Photoshop, Acrobat.
Demonstrated experience making independent decisions, analyzing situations, problem solving, and initiating action for laboratory maintenance. Ability to work independently.
Excellent communication and interpersonal skills. Interact p
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