Are you a hardworking and dedicated research professional interested in being part of breakthrough Research?
When you join Cedars-Sinai, you become part of a team that is at the forefront of medical advancements and life-saving medical and scientific breakthroughs. Cedars-Sinai is one of the leading institutes for driven research funding from the National Institutes of Health. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact.
Principal Investigator, Caroline Jefferies, PhD is searching for a Research Associate II to join the team!
The research of Caroline Jefferies, PhD, is focused on understanding the role that RNA/DNA sensing mechanisms in monocytes and neutrophils play in driving autoimmune disease. The lab's main area of focus is understanding these pathways in lupus, a debilitating, chronic autoimmune disease that presents as a broad spectrum of symptoms and manifestations.
The Jefferies Lab seeks a Research Associate II with an interest in performing routine and increasingly complex laboratory tasks and procedures. The RA II will develop technical expertise in one or more areas relevant to research projects and will participate in research activities involving all aspects of the research process, to include, but not limited to; investigation, technical, testing/validation of results, and report findings. The Associate will perform a variety of routine experimental protocols and procedures to support the objectives of laboratory research projects. The incumbent will observe and comply with safety standards and procedures, assist in preparation of data for publication and/or presentation at scholarly meetings, and assist in general laboratory maintenance. This position does not have supervisory responsibilities.
Primary Duties and Responsibilities:
Assists with the design of new complex or unusual protocols and techniques.
Keeps accurate and detailed records of experiments and results and helps in identifying and troubleshooting of unexpected results.
Orders laboratory supplies and supports laboratory operations.
Maintains lab equipment and related records and may coordinate use of lab equipment.
Assists in the operation of specialized equipment, as required by the area of research.
Orients Research Laboratory Assistants or lower-level Research Associates and undergraduate student researchers on day-to-day lab operations and routine procedures.
Will work with a team to characterize UV-induced skin disease in animal models on the following:
Conducting animal experiments to assess how UV contributes to skin disease in Lupus.
Setting up models to assess lung inflammation in lupus - including air liquid interface cultures, making precision cut lung slices to analyze inflammation.
Using co-immunoprecipitation and western blotting to look at protein-protein interactions and post-translational modifications of proteins.
Other laboratory analysis as appropriate such as RT-PCR, IF, and Western blotting.
Bachelor of Science or Bachelor of Arts degree in biological sciences, required.
Experience and Skillset:
Two (2) years of laboratory experience, required.
Familiar with routine laboratory procedures, experimental protocols, and overall lab organization.
Ability to work independently.
Must have outstanding interpersonal, communication and organization skills to work across company disciplines and functional units, and computer application experience.
Must possess digital literacy in Excel and Word.
Ability to simultaneously manage multiple tasks with attention to details.
Working Title: Research Associate II - Jefferies Lab - Rheumatology
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.