The Ajami laboratory is focused on advancing our understanding of the function and biology of the brains intrinsic immune cells: microglia and their counterpart; blood-derived macrophages. The main focus of our research is to understand the mechanisms that control the functional identity of different microglia subsets both in mice and human and to investigate the molecular basis of the immune response by these cells in different diseases of central nervous system (CNS). The research is built on our previous studies published in Nature Neuroscience that has contributed to a better understanding of microglia ontogeny and homeostasis in the adult brain ( Ajami et al 2007 ), contribution of peripheral immune cells to CNS diseases ( Ajami et al 2011 ) and identification of different subsets of microglia ( Ajami et al 2018 ).
Ample opportunities are available for collaboration with basic science and clinical departments within the School of Medicine and additional research units at OHSU, such as the Oregon Hearing Research Center (auditory neuroscience) and the Vollum Institute.
The laboratory of Dr. Bahareh Ajami is seeking a highly skilled and motivated molecular and cell biologists to join us as a postdoctoral fellow. The successful candidate will implement cutting-edge techniques such as mass cytometry (CyTOF), single-cell RNA sequencing, and multiplexed imaging analysis to make a significant impact at the forefront of translational neuroimmunology.
Work is generally 40 hours per week during normal working hours, however, some evening and weekend work will be required. Working with laboratory animals is required. Adherence to chemical and radiological safety ordinances is required.
Personnel will need to work at lab benches, biosafety cabinets, desks and/or cytometry instruments for up to 4 hours at a time. Ability to perform repetitive lab manipulations (gripping, grasping, reaching, twisting), move lab equipment under 25 lbs with accommodation, perform image analysis operation and help others with equipment use. Personal protective equipment must be worn as required. (Gloves, mask/respirator, eyewear, lab coat, etc).
Salary for this position aligns with the NIH Scale .
Doctorate degree in related field
Proficiency in writing scientific literature
Ability to prepare and present in scientific conferences
Competency in Molecular biology, cellular biology, flow cytometery techniques
Knowledge of handling mice
Knowledge of brain or immune system
Doctorate in Immunology, neuroscience, molecular biology
Knowledge of bioinformatics tools
Ability to code
Knowledge of biostatistics analysis, handling of human samples
Apply here online. Please be sure to upload a cover letter and Resume or CV.
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