This is a 100% limited position for 14 months that may be extended or converted to career status based on the needs of the department.
Chemistry and Biochemistry is one of the largest and most complex departments on campus. The department's organization is divided among three major research themes each with its own department leadership representation under the Department Chair: Biochemistry & Biophysics; Synthesis, Materials and Chemical Biology; and Physical, Analytical and Environmental Chemistry. The department is comprised of 70 ladder rank faculty, and additional 10 in various instructional titles and ~150 in academic research titles and postdoctoral scholars. The above academic community presents a plethora of diverse complex issues from Health Sciences Compensation Program agreements to adjuncts from national laboratories sharing negotiated employee patent agreements. The department is also comprised of 90 career staff; ~60 temporary or student staff, and 350 Master's and Ph.D. students. Undergraduate students majoring in chemistry number greater than 1,600, and total undergraduate and graduate annual course enrollments exceed 23,000. The department currently has more than 120 awards from federal, state and private sources for approximately $20 million per annum in extramural funding and $46 million in total annual expenditures.
The Department of Chemistry and Biochemistry manages eight recharge facilities supporting national as well as UCSD-wide research endeavors in academe and industry: Nuclear Magnetic Resonance, Molecular Mass Spectrometry, Biomolecular and Proteomics Mass Spectroscopy, Inorganic Characterization Instrumentation, Protein Crystallography, Small Molecule X-Ray Crystallography, Fabrication Facility plus the on campus Chemistry Storehouse. In addition, we are home to two national research center grants. The department also manages three major NIH training grants, and one Department of Education training grant, which fund graduate and postdoctoral students across UCSD departments/disciplines as well as off campus research organizations.
Incumbent will assist the Principal Investigator in conducting research and experiments on the detailed mechanisms of signaling pathways that lead to the regulation of gene expression by nuclear factor ºB(NF-ºB). Incumbent will analyze data, develop and optimize protocols, present in lab meeting and seminars, and participate in the preparation of scientific manuscripts based on experiments performed, when appropriate.
Independently conduct research with a wide variety of procedures such as in- tissue culture, transfection, cell-base assay development, maintenance of cell stock, plasmid preparation and quantification, protein expression and purification, Western blotting with quantification, immunoprecipitation and immunofluorescence, FACS analysis. As Laboratory Manager incumbent will be responsible for the day-to-day operations of the laboratory. This involves preparation of chemical solutions, laboratory maintenance duties; ordering and organizing supplies; assuring that lab equipment is kept is working condition; and safety, cleanliness, and organization of the laboratory. Incumbent will also be responsible ensuring recharge operations are correctly accounted for and billed. Interact professionally with faculty, postdoctoral scholars, students, collaborators, visiting scholars, and research technicians in laboratory.
Must be willing to work with hazardous chemicals and materials.
Strong theoretical and practical knowledge of chemistry and biochemistry, molecular biology, or genetics, including relevant laboratory techniques, acquired through a Bachelor's degree in chemistry, biochemistry, or related field; OR an equivalent combination of education and experience.
Extensive experimental experience performing standard and repetitive molecular biology techniques such as RNA and DNA preparation, molecular cloning, gel electrophoresis, PCR, etc.
Independent research skills with experience in experimental planning, execution, and analysis, troubleshooting and optimizing experimental procedures, and preparing figures and presentations.
Demonstrated skills to work with RNA as the primary experimental system
Strong experience with immunoprecipitation and immunofluorescence, FACS analysis.
Extensive experience in general laboratory techniques and molecular techniques including the ability to prepare solutions and use a pH meter
Independent experimental experience with microbiological and sterile techniques.
Excellent oral and written communication skills. Good interpersonal communication skills including tact, diplomacy, and flexibility with students, staff, facult
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.