Are you ready to be a part of breakthrough research?
Our Principal Investigator (PI), Dr. Joshua Goldhaber, MD is looking for a Postdoctoral Scientist to join his team!
When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report.
The laboratory of Joshua I. Goldhaber, M.D., Director of Basic Research Programs in the Smidt Heart Institute and Director of the Division of Applied Cell Biology and Physiology at Cedars-Sinai Medical Center in Los Angeles, CA is recruiting Postdoctoral Researchers. The Goldhaber lab studies the role of intracellular calcium cycling in cardiac pacemaking and excitation-contraction coupling in health and disease models, with a particular focus on the sodium-calcium exchanger and heart failure. The lab employs a variety of techniques including single cell patch clamp electrophysiology, high resolution voltage and calcium mapping, fluorescence photometry, laser scanning confocal microscopy, cardiac cell isolation, and various molecular techniques including transcriptomics and proteomics. The vibrant basic and translational research program in the Heart Institute at Cedars-Sinai, in addition to our existing relationships with UCLA, provides excellent opportunities for career development in cardiac research and mentoring for post-doctoral researchers.
Our studies require isolation of cardiomyocytes (ventricular, atrial, or sinoatrial node cells) or whole sinus node and atrial tissue sheets from either mice, rats or rabbits, patch clamping technique to study various ion currents, extensive use of a state of the art laser scanning confocal microscope to study subcellular calcium and other ion characteristics in live myocytes, immunostaining in fixed tissue, qPCR, western blotting, analysis and interpretation of data, preparing manuscripts and posters, presenting slide presentations at national meetings, and applying for fellowships and grants.
Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist, the Research Fellow will perform routine and complex laboratory procedures throughout training period. You may develop, adapt, and implement new research techniques and protocols. Will analyze and interpret data and may assist in preparation of grant proposals. Will participate in publications and presentations as author or co-author. You will not be responsible for generating grant funds.
Essential job duties and responsibilities:
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.
May develop, adapt, and implement new research techniques and protocols.
Analyzes, interprets, summarizes and compiles data.
Performs routine and complex laboratory procedures throughout training period.
Operates and maintains equipment and instruments.
M.D. or Ph.D. in biophysics, biochemistry, physiology, molecular biology, or related field is required
Hands-on experience with voltage/calcium imaging or patch clamping in cardiac cells
Additional experience in molecular biology, cell culture techniques and animal handling is strongly preferred
Must possess excellent good command of English language (written and spoken) and will be expected to write applications for extramural funding.
Applicants should have strong organizational skills and interact/collaborate well with other lab members.
Works independently on research projects designed by a mentor (typically the PI) within area of specialization.
Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment.
Prior experience in basic cardiovascular laboratory research.
Knowledge of Microsoft Word, Excel, GraphPad Prism and other Windows-based software.
Experience in grant proposal development and grant submission in basic research.
Ability to work independently.
Good written and verbal communication and interpersonal skills.
Working Title: Postdoctoral Scientist - Smidt Heart Institute - Goldhaber Lab
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.