The Bass Lab at the Herbert Irving Comprehensive Cancer Center (HICCC) of Columbia University is seeking a highly motivated, enthusiastic laboratory research technician (Technician B) to join our group. Our research group investigates the cancer genome to elucidate key biological processes and therapeutic vulnerabilities in carcinomas arising in the GI tract, with the greatest focus on the stomach and esophageal cancers. The research technician will work to identify and study oncogenes and tumor suppressor genes in gastrointestinal cancer and work to translate these findings into new therapeutic approaches. This individual will work with a research fellow to perform cutting-edge research with a potential impact on cancer treatment. We are looking for a person to join us in the late summer/early fall of 2021.
Specific duties will include:
Tissue culture of human cancer cells and organoid models.
Protein chemical assays including immunoprecipitation and immunoblotting.
Cell proliferation assays following pharmacological treatments.
Extraction and analysis of DNA and mRNA, including PCR, quantitative PCR.
Experience in mouse models may be involved, including mouse genotype and mouse colony maintenance.
Data analysis and recording of results electronically and in a lab notebook.
Protocol and literature searches.
Evaluations of new assay methods or instrumentation.
Working closely with a scientist who will serve as a direct supervisor and mentor.
Co-operating with a team of experimental and computational scientists.
Preparation of reagents and media used in lab experiments.
Operation and maintenance of standard lab equipment.
Oversight of laboratory safety protocols.
Management of a laboratory reagent database.
Bachelor's degree in chemistry, biology or physics or a completed animal husbandry program or equivalent in education, training, and experience. Knowledge of various related laboratory procedures and techniques preferred. One year of related experience preferred.
Preference will be given to those with at least one year of full-time laboratory experience in molecular and cellular biology but 2021 college graduates are welcome and encouraged to apply.
Ability to perform a variety of cellular and molecular biology techniques is essential for this role.
Ability to work well within a team, flexibility, and responsibility.
Good organizational, interpersonal, and communicational skills
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 514329
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.