Research - Laboratory/Non-Laboratory, Staff/Administrative
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The Division of Metabolism, Endocrinology, and Nutrition in the Department of Medicine has an outstanding opportunity for a full-time Research Scientist/Engineer.
The Research Scientist/Engineer will support the laboratories of Drs. Gregory Morton, Jarrad Scarlett and Michael W. Schwartz within the Division of Metabolism, Endocrinology and Nutrition at the University of Washington. Our research examines the role of the brain in the control of feeding and glycemic control and if defects in this system contribute to the development of obesity and diabetes. To accomplish this, we utilize state-of-the-art neuroscience and rodent surgical techniques in combination with comprehensive rodent metabolic phenotyping. This research is supported by funding from the NIH, the American Diabetes Association, DoD and support from Novo Nordisk.
The field of research this position is engaged in is Obesity and Diabetes. The purpose of the research projects this position will support is to investigate the biology of body weight and blood glucose control and causes of obesity and diabetes.
POSITION DESCRIPTION The major duties of this position include the performance of advanced stereotaxic surgery and other rodent surgical procedures. In addition, this position will include the performance of state-of-the-art neuroscience techniques including pharmacogenetics and fiber photometry and advanced rodent metabolic phenotyping. This position requires strong problem-solving skills and the ability to assist in the development and refinement of technical methodologies. The work is conducted in collaboration with lab trainees with additional oversight provided by the principal investigators. Other duties include the performance of standard rodent behavioral and metabolic phenotyping and handling and the performance of routine biological assays. In addition to the recording, collection, and organization, and analysis of data, this position will also have some administrative responsibilities associated with operation of the surgical suites.
SPECIFIC DUTIES AND RESPONSIBLITIES
Sterile rodent surgery (mouse and rat), including but not limited to: stereotaxic microinjection and fiber or cannula implantation, osmotic minipump implantation, transponder and implant surgery, and catheterization
Conduct chemogenetic, optogenetic and fiber photometry studies with data collection in collaboration with other staff and research fellows
Perform standard behavioral and metabolic phenotyping (GTT, ITT, etc)
Establish and validate surgical protocols, validate viral expression and targeting to include immunohistochemical validation, as needed.
Fabrication of specialized equipment as needed to support animal studies
Transcardial perfusion fixation
Ensuring that animal surgical suites are in compliance with IACUC and assist in coordinating and conducting surveys
Ensuring that all surgical equipment is functional and scheduling necessary repairs and calibrations
Routine inventory of general use items for surgery suites
Make purchases of general use surgical items for bulk stock
Monitoring and ordering of O2 and Nitrogen
Maintenance and repair of surgical tools and surgical equipment
Point person for Biohazards (animal suites)/ Biological Use Authorization
Oversight of laboratory laundry operations
Ensure DEA/DOH license and laboratory compliance is up-to-date (participate in laboratory inspections, coordinate drug purchases and pick-up, reverse distribution)
Participate in IACUC inspections and assist with Hoverboard protocol updates, as needed
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.
Bachelor's Degree in an appropriate field of science or technology plus two or more year’s experience in a related area or equivalent combination of education/experience.
Experience with performing rodent surgical procedures. Experience with performing behavioral and metabolic measurements in rodents. Experience with performing basic wet laboratory standard procedures. Experience with data collection, recording and organization of data for graphical tabular presentation.
Basic computer skills in Word and Excel.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Ability to work both independently and cooperatively with others including fellows, students, and staff.
Willing to learn new tasks and adapt to changing lab needs
Assist with all lab projects and experiments as needed, priority of which to be determined by the supervising PI
Prior experience working with surgical techniques and performing behavioral and metabolic measurements in rodents.
CONDITIONS OF EMPLOYMENT
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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