The Seattle Cancer Care Alliance (SCCA), located in Seattle, Washington, is part of a dynamic collaboration among three organizations known nationally and internationally for their patient care and research: Fred Hutchinson Cancer Research Center, University of Washington, and Seattle Children's. Over the past 25 years, these institutions have worked together to support their mission of adult and pediatric oncology patient care services, research and education.
The Cellular Therapy Lab (CTL) at the Seattle Cancer Care Alliance (SCCA) is on the cutting edge of new technologies for cancer therapy, including cell-based immunotherapy. We are committed to advancing treatment options for our patients through the translation of innovative research into clinical practice. We collaborate with our Alliance partners (University of Washington, Fred Hutchinson Cancer Research Center and Seattle Childrens Hospital) as well as industry (biotechnology) and non-industry external entities.
CTL is responsible for all minimally manipulated therapeutic cell processing occurring at the SCCA for standard therapies, clinical trials and commercial cell therapeutics. Procedures range from cryopreservation to flow cytometric enumeration of cell proportions to more complex procedures such as cell selections, including enrichment and depletion. The laboratory is regulated by the FDA cGTP/cGMP standards, maintains College of American Pathologists (CAP) certification, and is accredited by the Joint Commission and FACT.
This posting is for a Cell Therapy Specialist I/II/III depending on applicable qualifications. Candidates with no previous cellular therapy experience will have hands-on training in the lab. Employees must adhere to all SCCA policies and processes, including the SCCA Code of Conduct and all HIPAA privacy requirements.
Work Schedule: T-S, 9:30-6
Process cellular products/specimens according to standard operating procedure (SOP), and specific guidance for clinical trials/commercial products, using aseptic technique
Perform and analyze results of quality control testing of components, including automated nucleated cell counts and flow cytometry
Prepare reagents and materials for clinical procedures
Enter patient and specimen information and results in the Laboratory Information Management System (LIMS)
Document processing steps accurately, generate processing reports and prepare patient/donor laboratory charts; review processing reports and charts
Understand and stay current with SOPs as needed and perform SOP qualifications. Provide input/feedback toLab Supervisor on documentation and process improvements
Participate in new laboratory staff orientation, training, and competency assessments: ability to translate basic theory and practice to coach and teach other less experienced staff
Develop new or non-standard procedures and processes as needed
Assist with development and validation of equipment and processes
Thaw cryopreserved components and assist with infusion at the patient bedside
Meet unrelated donor (URD) component couriers and perform necessary testing and processing of components prior to release
Complete basic projects with minimal supervision
Builds constructive relationships across departments
May be asked to participate in inspections/auditing processes
Takes initiative to enhance scientific knowledge and acts as a technical resource in the lab
Takes initiative to suggest improvements/projects and participate
May act as subject matter expert in large, cross-department projects
Communicate and collaborate to share appropriate information with laboratory staff, Quality (QA), Cell Therapy Services (CTS), Administrative, Clinical Trial partners (e.g. PI and research lab staff) and additional CTP Leadership, as needed
Perform specialized operational duties
Perform cell selections:
CliniMACS cell selection e.g. CD34+ cell enrichment, CD3+ cell depletion
Assist with bone marrow collections as an optional, more specialized function at this level
3+ years of experience in a clinical cell therapy laboratory with increasing responsibility
Basic hematology and immunology knowledge
Knowledge of current Good Tissue Practices (cGTP) and knowledge of current Good Manufacturing Practices (cGMP).
Motivation and initiative to learn new scientific theory and applications
Ability to work well independently
Proven team player, demonstrating leadership capabilities to build relationships across departments
Collaborate and communicate effectively across functions
Ability to review data thoroughly, interpret objectively, communicate and discuss with others
Strong troubleshooting capabilities for both standard and complex (e.g. clinical trial) processes
Scientific writing skills, including preparation of clear, concise SOPs and technical reports
Strong math skills
Strong communication skills, both oral and written, including the ability to describe results to CTP Leadership and Principal Investigators
Flexibility in scheduling: nights, weekends, holidays and on-call rotations
Bachelors Degree in a science-related field preferred
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.