The Department of Chemistry and Biochemistry seeks to hire a Post-Doctoral Fellow to develop microbial heterologous expression systems via synthetic biology technologies, aiming to utilize the vast genetic potentials of the biosynthetic gene clusters from cultivatable microbes for production of bioactive natural products, such as antibiotics and anticancer agents. Following the establishment of a high efficiency heterologous expression system, the selected promising biosynthetic gene clusters will be cloned/synthesized and expressed in this heterologous expression system for production of the corresponding compounds. The production level and chemical diversity will be further tuned by genetic manipulation. In addition, the biological and/or physiological activities of the compounds discovered will be studied.
Additional job responsibilities include contributing to writing manuscripts and reports on funded projects and assisting in training graduate and undergraduate students in their research.
Advertised Minimum Qualifications :
PhD in Chemistry, Biochemistry, Biology or a closely related science with experience in microbial genetics, gene editing, and synthetic biology.
Full/Part Time: Full Time
Internal Number: 97139
About The University of South Carolina
The University of South Carolina System is comprised of the state’s flagship university in Columbia (founded in 1801 and currently one of the top 50 “Best Colleges” according to U.S. News and World Report), three regional comprehensive universities (USC Aiken, USC Beaufort and USC Upstate), and Palmetto College consisting of four two-year campuses (USC Lancaster, USC Salkehatchie, USC Sumter, USC Union and Fort Jackson/Extended University). Together, the USC System institutions offer more than 450 degree programs on campus and online and are uniquely positioned to meet the state’s educational, cultural, health and research needs. The System employs nearly 14,000 people who work daily to improve the lives of students, fellow South Carolinians and the world. Our diverse engaged faculty and staff enjoy a dynamic and intellectually stimulating work environment.