Research - Laboratory/Non-Laboratory, Staff/Administrative
Department: MED-Neurology Salary/Grade: NEX/11
Conducts experimental research lab work and/or assists in design of one or more specific phase(s) of entire project(s). May complete mathematical calculations, and/or computer tasks and/or assist in judging validity of data. Follows appropriate protocols, policies, procedures, regulations, Good Clinical and Good Laboratory Practices.
The main responsibilities of the incumbent are to oversee the mouse colony. We have multiple strains of mice (mice that have different genotypes) and multiple crosses are in process. The incumbent will maintain the parental strains, generates the crosses, confirm genotypes and supply animals of the appropriate age, sex and genotype to researchers in the lab. Participation in analysis of these animals is encouraged.
Following protocols, designs, sets-up and conducts basic experiments.
Analyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes, validity and/or accuracy.
Using a fully functioning level of skill, completes the following activities (please highlight):
DNA, RNA, Protein isolation, purification and expression
Southern, Northern, Western blotting
Cloning, mapping and sequencing of DNA
Recombinant virus production and purification
Cell culture, cell isolation
Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
ELISA, Elispot assay
Antibody production and purification
Breeding and screening transgenic mice
Database management of colony
Maintains detailed records of results which may include collecting, extracting & entering data.
Manipulates, interprets &/or presents results.
Prepares charts & graphs for presentations & publications.
Performs scientific literature searches in support of research.
Completes portions of grant applications, manuscripts & publications.
Tracks & summarizes lab supply expenses.
Orders &/or maintains inventory of reagent.
Performs other duties as assigned.
Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience.
Minimum Competencies: (Skills, knowledge, and abilities.)
Demonstrated laboratory experience, minimum of two years;
Demonstrated ability to follow detailed instructions as required by research protocols;
Demonstrated computer skills, including spreadsheets and basic computations;
Attention to detail and accurate record keeping;
Ability to work independently and in a team environment;
Preferred Qualifications: (Education and experience)
Interest in phenotype analysis
Preferred Competencies: (Skills, knowledge, and abilities)
Previous experience with mouse colony management and oversight
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 40645
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.