Pharmacology is the scientific discipline that studies the mechanisms by which drugs alter biological systems in an attempt to improve health and alleviate disease, whereas toxicology is the study of mechanisms by which drugs and chemicals in the environment produce unwanted effects. Together these disciplines encompass the molecular basis of drug action, the actions of drugs on cells, organs, and organisms, the genetic variations in drug action, and drug discovery.
Conducts a wide range of complex experiments in neuroimmunology, environmental neurotoxicology, and free radical biology with a degree of independence. Prepares reports and conducts analyses of performed experiments. Provides guidance and support to junior-level staff This laboratory is under the direction of Principle Investigator, Stark Professor, Michelle Block , Ph.D.
Primary Duties and Responsibilities
Perform complex techniques or procedures:
Cell biology (ex. flow cytometry & histology).
Microscopy (ex confocal & multiphoton microscopy).
Tissue culture (ex. primary & cell line cultures).
Molecular biology (ex. DNA & RNA, including cloning).
Animal Research: Experiments/Handling/Breeding (Mice & Rats), including a large colony of immunocompromised mice.
Equipment & laboratory maintenance.
Regulatory procedures/protocols (ex. IACUC, IRB, chemical safety, radiation safety, and controlled substances).
Management of large immuno-compromised mouse colonies.
Research team leadership:
Coordinate assignment of laboratory personnel.
Monitor completion of assigned tasks.
Provide training (ex. techniques, equipment use, and analysis) to research technicians, post docs, graduate students, and/or undergraduate students.
Serve as a resource to other laboratory personnel.
Direct or participate in the tabulation and computation of project results.
Prepare project research reports/analyses.
Write methods/results of experiments and assist in scientific writing for publication and grant submissions.
Review literature to identify suitable procedures and methods.
Communicate with collaborators to facilitate transfer of data, samples, and other materials.
Drive own individual research projects: data collection and analysis.
Collaborate on multiple research projects in the laboratory.
Design, perform, troubleshoot, and analyze pilot studies to develop protocols for the laboratory.
Assist the PI in grant applications: data, writing, and submission.
Maintain knowledge of scientific trends through readings, conferences, and seminars.
Bachelor's degree in a related field and three years of related work experience.
Mouse colony maintenance, or mouse handling experience. Proficient communication skills. Maintains a high degree of professionalism. Demonstrated time management and priority setting skills. Demonstrates a high commitment to quality. Possesses flexibility to work in a fast paced, dynamic environment. Seeks to acquire knowledge in area of specialty. Highly thorough and dependable. Demonstrates a high level of accuracy, even under pressure.
Master's degree. Degree in science. Experienced handling mice as part of a research process. Research experience. Chemistry or neuroscience background, in addition to significant cellular/molecular biology research and laboratory management accomplishments/experience.
Working Conditions / Demands
The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The role requires the ability to move objects weighing up to 25 pounds and will occasionally work near moving mechanical parts. The person in this role must be able to perform the essential functions with or without an accommodation.
Due to the COVID-19 pandemic, there may be differences in the working conditions as advertised in our standard job postings (e.g., the ability to travel from one campus to another, etc.). If you are invited for an interview, please discuss your questions or concerns regarding the working conditions at that time.
This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.
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About Indiana University Purdue University Indianpolis - IUPUI
Founded in 1820, Indiana University is the state’s public university system, comprised of two core campuses—IU-Bloomington and IUPUI—and six regional campuses located throughout the state. Combined, the total student population is more than 114,000 undergraduate, graduate and professional school students. IU is one of the largest employers in the state, with over 20,000 faculty and staff. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. Diversity and inclusion remains a core commitment to IU’s mission to cultivate an educational environment that supports equal access, participation and representation on all of its campuses and that provides educational and career opportunities for all.