Research - Laboratory/Non-Laboratory, Staff/Administrative
Life Science Research Professional 1
Job Number: 89144
Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments.
Stanford University, located in the heart of Silicon Valley, is one of the world's leading teaching and research universities. Since it's opening in 1891, Stanford has been dedicated to finding solutions to big challenges and to prepare students for leadership in a complex world. A laboratory in the Institute for Immunity, Transplantation and Infection (ITI) is seeking a highly motivated Life Science Research Professional 1 (LSRP 1) to join our team. ITI is an interdisciplinary institute and the overall goal of the lab's research is to understand how the innate immune system regulates adaptive immune responses to pathogens and harness this knowledge in the design of vaccines and therapeutics. Towards this end, we are using an integrative systems biological approach that use high throughput assays (transcriptomics, micro RNA expression, metabolomics) combined with computational approaches.
The LSRP 1 primary duty will be to perform DNA digests, genotyping using PCR, analysis via gel electrophoresis and visualization, compiling results and uploading to an on-line database system for a 70+ strain mouse colony and assist with mouse colony maintenance. The LSRP will also work with research personnel and will use a variety of knockout and transgenic mice to perform research experiments using molecular biology techniques which include PCR, genotyping, cloning, DNA extraction; biochemical assays, animal surgeries, cell culture techniques, histology, immunochemistry in animals. The goal of the work will be to further understand how the immune system works and to help develop the best approach to vaccine development. The LSRP will be expected to troubleshoot existing protocols and develop novel protocols and procedures as well as provide technical and scientific advice to other research personnel in lab.
Secondary duties will include lab maintenance to facilitate the work of the lab. The position will also entail lab support tasks including maintenance of lab records and adhering to safety regulations.
Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
Independently conduct experiments; maintain detailed records of experiments and outcomes.
Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
Tissue digestion and PCR to genotype many mouse strains, analysis of results after gel electrophoresis and visualization, compilation and entry of results in a database
Design primers for genotyping experiments
Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned.
B.S. in Molecular Biology, Genetics or similar field or a related scientific field.
Experience with PCR and gel electrophoresis.
Knowledge of basic biology and molecular biology/genetics.
Skills to coordinate activities between units and investigators, and to consult with investigators regarding their research projects.
Some background in mammalian genetics and gene editing techniques.
Excellent organizational and planning skills using computerized data bases for scheduling procedures, time management, data entry, graph preparation, etc.
Ability to work efficiently within an on-line database system.
Some prior experience working with mice.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
Ability to maintain detailed records of experiments and outcomes.
General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
Ability to work under deadlines with general guidance.
Excellent organizational skills and demonstrated ability to accurately complete detailed work.
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
Must have correctible vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
Will require working in close proximity to blood borne pathogens.
Will require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.
Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.
Location: School of Medicine, Stanford, California, United States Schedule: Classification Level:
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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Located between San Francisco and San Jose in the heart of Silicon Valley, Stanford University is recognized as one of the world's leading research and teaching institutions. Leland and Jane Stanford founded the University to "promote the public welfare by exercising an influence on behalf of humanity and civilization." Stanford opened its doors in 1891, and more than a century later, it remains dedicated to finding solutions to the great challenges of the day and to preparing students for leadership in a complex world. The University's thriving diverse community is comprised of nearly 7000 undergraduate students, 12000 graduate students, 2000 faculty members, 1900 postdoctoral scholars, and over 11,000 academic and administrative staff in seven schools including several interdisciplinary research centers and institutes. The campus spreads over 8000 contiguous acres and nearly all undergraduates live on campus. Stanford offers bachelor's and master's degrees in addition to doctoral degrees (PhD, MD, DMA and JD) plus a number of professional and continuing education programs and certifications. More at http://facts.stanford.edu and http://www.stanford.edu. Stanford is an equal empl...oyment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford also welcomes applications from others who would bring additional dimensions to the University’s research, teaching and clinical missions.