Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
Research: Radiopharmaceutical Imaging (Sharma) and Translational Neuropsychopharmacology (Wong) Laboratories
Research interests of our laboratories are focused on the discovery, development, preclinical validation (radiotracer cell bioassays, preclinical imaging including live cell imaging using fluorescent counterparts of lead agents) and translation of well-validated leads for nuclear medicine imaging. We are seeking a radiochemist with expertise in design and development of heterocyclic small organic molecules (incorporated with F-18/C-11) for PET imaging. This position seeks a candidate with experience in cGMP production, including development of standard operating procedures and quality control procedures used in synthesis of radiotracers for human use. This position also requires prior experience in developing bioassays for testing of new molecular imaging probes in preclinical disease models and translation of lead agents into human research. It is anticipated that human research studies of targeted agents would involve interactions with an interdisciplinary team of investigators in neuroscience, cardiovascular, and pulmonary sciences including tumor biology. Therefore, we seek a candidate with outstanding communications skills (oral and written). Labs of both PIs (Drs. Sharma & Wong) offer a strong research platform for interfacing preclinical translation research with human imaging.
PRIMARY DUTIES AND RESPONSIBILITIES:
Assist in production of new PET tracers under GMP conditions for developing SOPs and CMCs for submission of IND applications for FDA approvals.
Design and synthesis of new heterocyclic molecules for biomedical imaging applications (neuroscience, cardiovascular imaging, inflammation, and tumor biology).
Assist with ongoing PET/SPECT/Optical imaging research studies and bioassays for preclinical translational imaging.
Work with other interdisciplinary scientists and radiochemists to develop and optimize radiotracer production methodologies for current and ongoing human PET studies (Wong and Sharma labs).
Perform miscellaneous radiochemistry related tasks as assigned.
Ph.D. degree in medicinal organic chemistry or doctorate in a related discipline.
At least two years of postdoctoral experience in a radiochemistry/cyclotron laboratory producing novel radiotracers for preclinical and clinical use.
Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
Applicant Special Instructions:
Interested applicants should send a CV with contact information of references and cover letter (describing relevant expertise and scientific interests) to both Dr. Dean Wong at firstname.lastname@example.org and Dr. Vijay Sharma at email@example.com.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Department Name/Job Location:
This position is in the Department of Radiology. This position is for the Medical School Campus.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.