Research - Laboratory/Non-Laboratory, Staff/Administrative
The Macklis Lab is directed toward (1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-circuit formation, and degeneration in the cerebral cortex and (2) applying developmental controls toward both brain and spinal cord regeneration and directed differentiation for in vitro therapeutic and mechanistic screening.
Under the direction of the Principal Investigator and senior lab personnel, the research assistant will support research activities in one or more of the following areas:
molecular biology, including cloning and CRISPR gene editing;
mouse genetics, husbandry, behavior, neuroanatomy, and surgery;
cell culture, including directed differentiation of stem cells into neurons and brain organoids;
microscopy, tissue processing, CLARITY, and image analysis.
Working within specific guidelines and under specific direction from supervisors and other research staff, Research Assistant will:
Perform laboratory experiments using developed approaches. Assist in the design of laboratory experiments, techniques, protocols, and new approaches;
In coordination with senior lab personnel, maintain and genotype mouse lines and/or mammalian cell cultures;
Analyze experimental data, and troubleshoot experimental protocols to ensure successful and timely project completion;
Document, compile, and assist with interpreting experimental data. Report data to supervisor and team;
Process, organize, and summarize data using scientific, word processing, statistical software applications, and the Adobe creative package;
Participate in weekly lab meetings and journal clubs;
Instruct and assist other staff and students in basic laboratory techniques including standard molecular biology techniques, cell culture techniques, microscopy, and/or animal care;
Perform related lab duties such as maintaining and cleaning equipment, preparing common stock solutions, maintaining the animal colony, assisting in the acquisition of animals, and ordering supplies.
This is a grant-funded two-year term position with the possibility of extension based on satisfactory performance and the continued availability of funding.
May be required to work with and handle lab-based animals May be required to lift, move and transport related laboratory equipment. May be required to work with a variety of hazardous materials.
We invite individuals with diverse backgrounds, experiences and abilities to be a part of our community.
The Department of Stem Cell and Regenerative Biology and the FAS are committed to cultivating not only the diversity of our faculty, staff, and students but also in developing an inclusive culture that is vibrant, engaging and encouraging of innovation as well as intellectual debate. We believe creating and maintaining an inclusive workplace allows employees from all backgrounds and walks of life to achieve their fullest potential. We also believe an inclusive culture is one that accepts, values and views as strength the difference we all bring to the workplace. We encourage our community members to participate in our FAS Diversity Dialogues.
Salary Grade: 052
Union: 55 - Hvd Union Cler & Tech Workers
College level coursework in -biological sciences and at least one year of lab experience with molecular biology, cell culture, surgical techniques, laboratory animals, and/or microscopy.
Excellent communication, organization, and time management skills.
High level of initiative and motivation; ability to work independently and with a team.
Attention to detail, especially in regard to executing experimental protocols.
Ability to think creatively to solve problems.
Experience in one or more of the following is preferred: brain development, gene editing technology, animal handling, surgical techniques, stem cell culture, and microscopy techniques.
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 53536BR
About Harvard University Faculty of Arts and Sciences
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.