Junior, Assistant, or Associate Specialist - Tward Lab
The Tward lab in the Department of Otolaryngology, Head & Neck Surgery is looking for people interested in a Specialist position (Junior, Assistant, or Associate rank) at UCSF. We are an interdisciplinary lab. Specialists appointed at the junior rank must possess (or in process of obtaining) a bachelor's degree, preferably in the fields of biology, bioengineering, biochemistry, computer science or related disciplines. Specialists appointed at the assistant/associate rank must have (or in process of obtaining) a master's degree, preferably in the fields of biology, bioengineering, biochemistry, computer science or related disciplines. Applicant’s materials must list (pending) qualifications upon submission. Applicants must have obtained the degree requirement for the Specialist rank by the time of hire.
The ideal candidate will have familiarity with one or more of the following: animal handling, microscopy, molecular biology, mammalian cell culture, instrumentation, genome editing/CRISPR technology, and quantitative and computational analysis. We prefer candidates with a strong background in bioinformatics/computational biology who have the ability to perform independent research in addition to supporting the lab. Candidates interested in working in the lab for at least two years are preferred.
Our lab is interested in the identity and function of the molecular events that reprogram a normal cell into a pre-cancerous cell and ultimately to a cancer cell. We hope to harness that knowledge to generate novel therapies. We use a variety of techniques to address these questions such as high throughput sequencing of clinical samples, cell culture and in vivo modeling, and computational analysis of large, multidimensional data sets. For example, we have identified a set of mutations in head and neck squamous cell cancer that we are highly confident contribute to the initiation and progression of the disease, however how these mutations interact and how they reprogram cells is largely unknown. We have generated models of these diseases using CRISPR-Cas9 technology in primary human tissue to create “designer” tumors that recapitulate the diversity of human squamous cell cancers.
We additionally have a strong interest in the organs of hearing. We have used single cell RNA-seq technology and genetically modified animals to develop a cellular map of these organs and understand how the cells of these organs develop.
Applicants must apply online with CV (must list previous research experience and GPA on CV), Cover Letter, List of Prior Coursework, and the contact information for three references at https://aprecruit.ucsf.edu/JPF03307.
UC San Francisco seeks candidates whose experience, teaching, research, and community services has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status
Internal Number: JPF03307
About University of California, San Francisco
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.