The Hemophilia and Thrombosis Treatment Center, University of California, San Diego (UCSD), Department of Medicine is an innovative, multi-disciplinary program catering to the needs of adults and adolescent patients and their families with hemophilia, von Willebrand Disease, and other bleeding and thrombotic disorders.
The Hemophilia Thrombosis Research Program is directed at advancing new therapies, evaluating novel aspects in hemophilia care, and creating new knowledge about the evolving needs of the aging patient with hemophilia.
PhD, MD, or PhD/MD to work in a translational hemostasis and thrombosis research lab studying the pathobiology of joint disease in hemophilia. The ideal candidate should have interest in 1) protein biology and coagulation, applying a broad range of biological techniques, 2) analysis of RNAseq and/or proteomics data sets, and 3) animal models, ideally in the area of hemostasis/coagulation or arthritis research. Our goals are to study the pathobiology of hemophilic joint disease, as well as the effects of novel clotting factor and non-factor compounds for their effects on bleeding, iron handling, and inflammation in hemophilic joints.
The candidate should be able to take initiative and to work independently with appropriate supervision and guidance in a basic scientific, multi-disciplinary setting including protein biologists, imaging specialists, bioinformatics personnel and clinicians, combining basic scientific and translational aspects of disease. He or she will be responsible for in vitro and in vivo characterization of biological pathways involved in joint disease including analysis of RNAseq and proteomics data sets, utilizing animal models and human samples. Experience in, or interest to acquire knowledge in respect to bioinformatics analyses using R-software is essential. This postdoctoral fellowship will provide a unique opportunity to advance into the biological aspects of hemostasis and inflammation in hemophilic joint disease by studying novel compounds and paradigms in biological assays, large data set analyses and animal models. The Fellow will work with mice and human samples and develop a strong translational component for application in human disease.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.