Cedars-Sinai Biomanufacturing Center (CBC) is a new 22,000 square feet, state-of-the-art biomanufacturing facility located in West Hollywood, California. The CBC comprises a cGMP cell manufacturing facility housing multiple cleanroom cell production suites and process development rooms for producing the next generation of cell and gene therapies. These new therapies will be used for human IND-enabling clinical trials. With combined expertise in a cGMP-compliant approach to manufacture cells at scale, the CBC will overcome many challenges by building innovative technologies, connecting protocols, up-scaling of processes and achieving Food and Drug Administration standards for all steps involved to bring innovative cell therapy solutions to researchers and translation scientists. With our world-class expertise in stem cell (iPSC) biology, bioprocessing, translational medicine and manufacturing, the CBC is providing a much-needed biomanufacturing center in Southern California! To learn more, please visit: Biomanufacturing Center | Cedars-Sinai (cedars-sinai.edu)
The Biomedical Technician participates on projects to develop and achieve goals related to various projects. Performs tasks associated with the project in accordance to established standard operating procedures (SOP). Responsible for maintaining lab equipment and performing lab maintenance duties including cleaning, sterilization and keep maintenance records. Performs activities strictly according to SOPs, with accurate documentation, and assists cross functional teams with required testing activates as needed. Contributes to the success of projects by keeping accurate and detailed records of experiments and results and will be expected to help supervisor generate reports.
Primary Job Duties and Responsibilities:
Performs a variety of cGMP manufacturing production and process development tasks for multiple clients following standard operating procedures for manufacturing processes that will be different for each project based on the types of cells, tissues or organs.
Performs tissue culture and aseptic techniques for developing and processing clinical grade and research grade cellular products in accordance to established standard operating procedures (SOP).
Performs cellular, micro- and molecular biology procedures including, but not limited to Western blot, Northern blot, DNA/RNA, Polymerase chain reaction (PCR), protein extraction, cell culture, immunohistochemistry, and staining.
Assists with process development, validation, and qualification for cellular production for multiple cell lines in GMP/good laboratory practice (GLP) environment.
Prepares cell culture rooms and research space, including cGMP production rooms, maintains material inventories, and places orders for equipment and supplies.
Writes and maintains good documentation in laboratory notebooks, data record/transfer, SOPs, and batch records.
Drafts standard operating procedures and maintains computer database.
Verifies samples received, logs samples into systems, and transports to appropriate environment within the facility for storage following SOPs.
Performs lab maintenance duties, including glassware cleaning and sterilization.
Maintains lab equipment and related records.
Prepares cGMP production room, maintains material inventories, and places orders for equipment and supplies
Assists in the operation of specialized equipment and machinery.
Ensures all activities comply with regulatory guidelines and safety standards.
Assists with tasks as needed.
Minimum of a Bachelor's Degree in Molecular Biology, Biochemistry or related science/engineering field.
Experience and Skillset:
One (1) year of experience in a lab environment or industrial setting.
Previous experience working in an aseptic environment, biosafety cabinet and working with human and animal tissues.
Working Title: Biomedical Technician - Research & Development
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.