Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
Post Doc Instructions:
Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.
Department Name/Job Location:
This position is in the Department of Internal Medicine, Division of Infectious Diseases. This position is for the Medical School Campus.
Doctoral degree (Ph.D. or MD/Ph.D.)
Willingness to conduct research using mouse models.
Strong written and oral communication skills, as evidenced by prior publications and presentations.
Ability to work independently and communicate with laboratory staff and investigators.
Previous research experience in virology or immunology.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Interested candidates should send a CV and list of three referees to:
Liang Shan, Ph.D. Assistant Professor Department of Internal Medicine Washington University School of Medicine St. Louis, Missouri Email: firstname.lastname@example.org
Internal Applicant Instruction:
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
The Washington University School of Medicine, Department of Internal Medicine has an immediate opening for a postdoctoral research associate interested in HIV infection and viral-specific human immune responses. The position is supported by an NIH grant in the Liang Shan laboratory. This position will provide an excellent opportunity for the candidate to pursue a career in the field of virology/immunology.
HIV-1 has high mutation rates and exists as mutant swarms within the host. Rapid evolution allows the virus to outpace the host immune system, leading to viral persistence. In patients who received antiretroviral therapy (ART), HIV-1 persists in a latent form primarily in quiescent CD4+ T cells and possibly tissue macrophages. Immune escape variants achieved in the latent viral reservoirs present one of the major obstacles to HIV-1 eradication. To date, no broadly applicable strategy has been developed to prevent or eradicate HIV-1 infection. Our studies involve a combination of biochemical, cell biological, and physiological approaches aimed at understanding the immunobiology of HIV infection and training the human immune system to better control and/or clear HIV-1 infection. Our current research includes the roles of CARD8 inflammasome in HIV-1 infection, control of HIV-1 infection by NK cells and macrophages, novel immunotherapeutic strategies for eliminating HIV-1 reservoirs using humanized mouse models.
Applicant Special Instructions:
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.