Research - Laboratory/Non-Laboratory, Staff/Administrative
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Our goal is to identify and study the transcriptional drivers that join forces to collectively activate networks of regulatory elements in the genome of acute lymphoblastic leukemia in order to develop novel targeted therapies that are more effective and less toxic than current medicines. We use genetically engineered mice, primary human leukemia samples, and cell lines as model systems. See https://chiangmarky8.wixsite.com/chiang-lab. The lab manager position is suitable for individuals who enjoy running their own projects and lab management/organization. If he/she desires, this position could be modified for those individuals who desire concentrated training in biomedical research to become highly competitive for graduate school or medical school. For such individuals, authorship on papers, traveling to research conferences, reading the literature and scientific presentations, and shadowing the PI in hematology clinic are among the many opportunities. The lab manager will also assist graduate students/postdocs and supervise undergraduate students in research projects.
Experimental duties include, but are not limited to, the following: * Breeding and management of the mouse colony * Bone marrow transplantation and Intrathymic injections * Histopathological analysis of leukemia * Retrovirus/lentivirus generation and transduction of cancer cells * Oncogene knockdown with CRISPRi and RNAi * High speed flow cytometry and cell sorting * ChIP, co-IP, qPCR, Western, and reporter assays * Tissue culture and Recombinant DNA Cloning
Non-experimental duties (10% of time) include, but are not limited to, the following: * Purchasing of laboratory supplies and equipment * Maintenance of laboratory equipment * Preparation of solutions and media * Preparation and maintenance of frozen stocks * Accurate record keeping * Interaction with regulatory agencies
Bachelor’s degree or higher in biomedical science and 1-2 years experience.
Experience in mouse handling or protein biochemistry or transcriptional genomics is required.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 194382
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.