The individual will be a key personnel responsible for research conducted. This position requires knowledge of basic laboratory procedures and record keeping and experience in zebrafish rearing and husbandry. The research assistant I will support ongoing research utilizing zebrafish genetics. Motivated individuals will have their own projects. Additional responsibilities will include maintenance of common lab supplies including buffers, organizing chemical stocks etc.
The Program in Molecular Basis of Genetic Diseases will use the tools of biochemistry and biophysics to understand how variations in the DNA of individuals are related to phenotypes. Our overall approach spans the spectrum from basic biochemistry, structural characterization of the target proteins using X-ray crystallography, electron cryo-microscopy (cryo-EM) and Electron Paramagnetic Resonance (EPR), to the generation of model organisms such as Zebrafish of the gene in question. A repertoire of biophysical and biochemical methods such as analytical ultracentrifugation (AUC), multiage light scattering (MALS), Isothermal titration calorimetry (ITC), surface Plasmon resonance (SPR) and crosslinking are integrated with structural biology to generate detailed mechanistic models of how mutations affect protein function.
Duties and Responsibilities
Manage and maintain inventory of lab reagents and equipment
Maintain zebrafish lines
Carry out transgenesis and genome editing (such as CRISPR/Cas9) in zebrafish
Genotype zebrafish lines
Other duties as assigned
Bachelor's degree in a related field is necessary.
Experience in molecular biology and cell culture is strongly preferred.
Experience in zebrafish rearing and husbandry is strongly preferred.
Commitment to Equity, Diversity, and Inclusion
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.
Vanderbilt University is an equal opportunity, affirmative action employer. Women, minorities, people with disabilities and protected veterans are encouraged to apply.
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.
Internal Number: 10000064
About Vanderbilt University
Vanderbilt University is a center for scholarly research, informed and creative teaching, and service to the community and society at large. Vanderbilt will uphold the highest standards and be a leader in the quest for new knowledge through scholarship, the dissemination of knowledge through teaching and outreach, and the creative experimentation of ideas and concepts. In pursuit of these goals, Vanderbilt values most highly intellectual freedom that supports open inquiry, equality, compassion, and excellence in all endeavors.