Research - Laboratory/Non-Laboratory, Staff/Administrative
The research lab of Dr. Michael Holinstat in the Department of Pharmacology at the University of Michigan, Ann Arbor, MI is in search of a Research Laboratory Specialist Senior. As the selected candidate you will utilize a number of in vivo animal microscopy techniques to investigate platelet activation and real-time regulation of blood clotting, hemostasis, and thrombosis in a number of arterial and venous injury conditions. You will be afforded the ability to work in an open-lab environment with access to all of its state-of-the-art equipment including both an in vivo intravital confocal microscope and an in vivo intravital fluorescent microscope in order to gain a greater understanding of hemostasis and thrombosis in the in vivo, setting in small animal models.
The lab maintains state-of-the-art hemostasis and thrombosis facilities including lumi-aggregometers, flow cytometers, hemavet, a microscopy facility containing 2 zeiss microscopes with the capacity for in vivo intravital confocal microscopy and single-cell high resolution microscopy, PCR machines, 2 multi-mode plate readers, and a phlebotomy suite with full-time phlebotomist. The lab is situated in the heart of Michigan Medicine within steps of a multitude of research resources and easy access to collaborators, the clinics, and animal facilities.
This position is for an experienced research specialist to work on preclinical and translational research projects focuses on thrombosis and hemostasis. The lab functions in a collaborative work environment with access to all of the state-of-the-art equipment in order to gain a greater understanding of signaling in the platelet, hemostasis and thrombosis in the in vitro, ex vivo, and in vivo setting in both human and mouse models. As the selected candidate your essential function will be to perform the day-to-day-operation of using intravital fluorescent microscopy to study blood vessel function and clotting, as well as, designing and executing laboratory experiments, and applying standard scientific protocols to experiments and research.
A PhD in pharmacology, physiology, biochemistry, molecular biology, or other related biomedical discipline
A minimum of 5 years of laboratory experience working with microvascular surgical techniques in mouse models
Experience working with small animals
Digital image acquisition involving real-time in vivo assays and analysis and interpretation of data
In order to be considered for this position, the applicant must have met or will have met all the required qualifications prior to the start date of employment.
Experience in intravital microscopy looking at vessel hemostasis and thrombosis in the mouse model
Experience with flow cytometry, western blot techniques, and working in a team environment
An understanding of lipid biology, protein chemistry, biochemistry, pharmacology, and signal transduction
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 194326
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.