The Theodorescu Lab at Cedars-Sinai is looking to hire a postdoctoral researcher with a strong background in cancer immunology. In this project you will be characterizing the tumor microenvironment of bladder cancer, with emphasis on mechanisms of immune-evasion orchestrated by tumor cells while also identifying immune system agonists or antagonists that modulate tumor behavior in vivo. To dissect cancer-specific vulnerabilities, we will combine techniques of biochemistry, molecular biology, and Crispr/Cas9 technologies, together with the use of innovative mouse models we have developed. A recent example of the type of work that will be undertaken is our papers by Guin ( J Natl Cancer Inst. 2014;106(5) ) and Tu ( SCIENCE Adv. 2019; 20;5(2) ) and associates. Our final goal is to identify novel biomarkers and interventions for cancer that will improve patient outcomes.
This individual would join our exciting cancer research group. The successful candidate will be a driven, creative, team-oriented individual with a passion for helping to discover and move fundamental cancer biologic findings towards a clinical setting. We employ many different in vitro and in vivo approaches and seek individuals with a strong background in cell and molecular immunology. We welcome applications from both recent PhD or MD/PhD recipients and individuals seeking additional postdoctoral training. Strong preference will be given to individuals with an outstanding publication record from their prior graduate and/or postgraduate training and/or existing extramural funding. For more information please visit:https://www.cedars-sinai.edu/Research/Research-Labs/Theodorescu-Lab/
Essential job Duties and Responsibilities:
Designs and performs experiments. Keeps detailed experimental records and documentation and analyze the results with the Principal Investigator.
Develops, adapts, and implements new research techniques and protocols.
Analyzes, interprets, summarizes and compiles data.
Performs routine and complex laboratory procedures throughout training period.
Assists in preparation of grant proposals, but is not responsible for generating grant funds.
Participates in publications and presentations as author or co-author.
Meets with PI on a regular basis to discuss research progress and plans.
May be asked to write small grant proposals or NRSA/T32 applications.
Spends about 75% of time on bench research experimentation and 25% of time on writing articles/analyzing data/online research.
Education and ExperIEnce requirements:
Doctorate (PhD or MD/PhD) in immunology or area directly related to field of research specialization.
Ability to work semi-independently on research projects within an area of specialization.
Thorough technical and theoretical knowledge of research project and the objectives to be accomplished during the one to five (1-5) year post-doctoral appointment.
Demonstrates aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.
Working Title: Postdoctoral Scientist - Theodorescu Lab - Cancer Institute
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.