Under the supervision of the Principal Investigator, the Senior Technician will be responsible for carrying out fully planned experiments to study the molecular and cellular mechanisms of neurodegenerative disease in mouse models.
Use conventional biochemical, molecular, cellular, immuonohistochemical, and behavioral assays.
Maintenance of mouse colonies, behavioral monitoring of mice, genotyping, drug or gene delivery via ICV/IP injections, tissue dissection, immunohistochemistry and confocal microscopy.
Responsible for ordering, preparing solutions, and performing other duties necessary to the functioning of the laboratory.
Laboratory management, mouse colony maintenance, and experimental work on research projects assigned by the PI to be performed either independently or in collaboration with postdoctoral research scientists and graduate students.
Dissection of mouse tissue, immunohistochemistry and confocal microscopy.
Perform other lab related duties necessary to the functioning of the laboratory.
Bachelor's degree and at least one and one-half years of related experience or equivalent in education, training and experience. Knowledge of various related laboratory procedures and techniques required.
Prior experience with neonatal mouse tissue dissection and immunohistochemical analysis of brain, spinal cord and muscle with cryostat and vibratome sectioning combined with confocal microscopy is highly preferred.
Training and experience in mouse colony handling and histology.
Bachelor's degree in biology or neuroscience.
Excellent interpersonal and organizational skills, demonstrated attention to detail, and ability to work independently. Strong knowledge of laboratory equipment and ability to keep accurate records.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 507985
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