The Keller lab in the Department of Pathology, Microbiology and Immunology at the School of Veterinary Medicine at UC Davis has a post-doctoral position opening aimed at characterizing adaptive immune responses in animals using high-throughput methodologies. The candidate will focus on establishing phage immunoprecipitation sequencing (PhIP-seq) to characterize antibody responses to viral pathogens and autoimmune antigens in animals. This includes phage library design, library generation, immunoprecipitation, next generation sequencing library preparation and interpretation of sequencing data. Other employed methods are ELISA, single cell RNA-seq and B- and T-cell receptor sequencing. The candidate will work closely with researchers and clinicians from different fields and specialties.
Ongoing project & research topics include:
Antibody responses to coronaviruses including SARS-CoV-2 in different animal species
Antibody responses to viruses in dogs
Identification of autoimmune targets in dogs
Immune repertoire profiling in spontaneous diseases of companion animals
Design and execute experiments, interpret and document outcome
Present research findings in the form of seminars, publications, etc.
Support graduate and undergraduate students in the laboratory
UC Davis is the home of the Aggies — go-getters, change makers and problem solvers who make their mark at one of the top public universities in the United States. Since we first opened in 1908, we’ve been known for standout academics, sustainability and Aggie Pride as well as valuing the Northern California lifestyle. These themes are woven into our 100-plus-year history and our reputation for solving problems related to food, health, the environment and society.Our 5,300-acre campus is in the city of Davis, a vibrant college town of about 68,000 located in Yolo County. The state capital is 20 minutes away, and world-class destinations such as the San Francisco Bay Area, Lake Tahoe and the Napa Valley are within a two-hour drive.