Research - Laboratory/Non-Laboratory, Staff/Administrative
Rutgers, The State University of New Jersey is seeking a motivated Postdoctoral Fellow for the Department of Pharmacology, Physiology and Neuroscience within the New Jersey Medical School.
A Postdoctoral position is available in the laboratory of Dr. Hyung Jin Ahn. Under the direction of the PI, the Post-Doctoral Fellow will conduct research studying the crosstalk between the cerebrovascular system and the nervous system to understand molecular mechanism underlying cerebrovascular deficits in Alzheimer's disease (AD). Increasing evidence suggests that cerebrovascular dysfunction is one of the pathological hallmarks of this disease. AD patients suffer from cerebral microinfarcts and a damaged cerebral vasculature, and a majority of patients with dementia present with both AD and vascular pathologies. Furthermore, some cerebrovascular symptoms such as white matter hyperintensity, start to increase 5 – 10 years prior to cognitive impairment onset. Circulatory deficiencies could therefore play an important role in AD progression, but the mechanism underlying the vascular contribution to AD is still unclear. Based on this idea, we are investigating the crosstalk between the cerebrovascular system and the nervous system to identify molecular targets and biomarkers underlying cerebrovascular deficits in AD. The individual will be primarily engaged in conducting experiments focused on identifying molecular mechanism underlying cerebrovascular deficits in AD pathogenesis, using fiberoptic spectroscopy combined with chemogenetics, MRI and immunohistochemistry in genetically modified mouse/rat AD models. Some of the projects involve collaborations with researchers at Rutgers Brain Health institute, The Rockefeller University, and Weill Cornell medical college. The individual will be responsible for planning and executing experiments independently.
Among the key duties of this position are the following:
Performs various research and technical operations relative to ongoing investigatory activities of a laboratory; may conduct independently or as assigned, specialized research for a particular project.
Participates in the development of performance standards, selection of methodology and instrumentation and coordination of the analytical and instrumentation functions with research areas to ensure conformance with the goals and objectives of the research program.
Assists in the conducting of continuous program of research and development regarding new procedures and instrumentation functions of the laboratory.
As requested, assists in the implementation of the programs and projects in special areas of interest to the overall research program of the laboratory.
Performs highly skilled biochemical, molecular biology, fiberoptic spectroscopy combined with chemogenetics, and immunohistochemistry using genetically modified mouse/rat AD models.
Contribute to writing manuscripts and review articles that directly results from his/her research.
Maintains a proper data notebook pursuant to the standards of the Department and the PI.
Assists in training and mentoring graduate students and technicians.
Minimum Education and Experience:
Ph.D. or an M.D with research experience in Neuroscience or Biomedical/Bioengineering.
The candidate is expected to be proficient in spoken and written English.
Ability to perform each essential duty satisfactorily and be able to work independently.
Posting Number: 20ST2085
Location: Newark (RBHS)
Internal Number: 122495
About Rutgers University
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.