The Computational Cancer Biology Laboratory (Azizi Lab) and the Laboratory for Synthetic Organogenesis (Simunovic Lab) at Columbia University are jointly seeking a passionate and self-driven senior research assistant with a background in molecular biology, cell culture, biochemistry or bioengineering, and wet-lab experience, and work on ongoing research projects and assist with lab management responsibilities.
The Azizi and Simunovic labs are located in a shared space at Columbia Biomedical Campus surrounded by a highly dynamic and multidisciplinary research environment, with direct access to state-of-the-art stem cell, microscopy, and sequencing facilities. The Azizi lab research aims to address impactful questions around characterizing heterogeneity in the tumor microenvironment and underlying mechanisms of response to immunotherapies. Towards this goal, the wet lab works on single-cell (transcriptomic, epigenetic, TCR, etc) profiling of patient samples from different cancer types. The experimental lab closely interacts with the computational component of the lab in an exciting interdisciplinary environment with members from diverse backgrounds and skill sets. The Simunovic lab focuses on applying bioengineering techniques to stem cell biology and developmental biology, so to understand the mechanisms underlying key milestones in embryonic development and disease. The lab uses human embryonic and patient-derived stem cells to mimic embryogenesis and organogenesis in vitro.
Both labs are part of the Fu Foundation School of Engineering and Applied Sciences. Azizi lab is affiliated with the Biomedical Engineering Department, the Irving Institute for Cancer Dynamics at Columbia University, and the Herbert Irving Comprehensive Cancer Center. Simunovic lab is affiliated with the Department of Chemical Engineering and the Department of Genetics and Development.
(95%) Work on ongoing research projects and assist with lab management responsibilities, as directed by the Lab Director / PI. Collaborate with other labs / PI's under the direction of the Lab Director / PI.
(5%) Perform other duties and responsibilities, as directed by the Lab Director / PI.
Bachelor's with 3+ years of wet-lab experience
Skills and Knowledge:
Experience with molecular biology and genetic engineering techniques, high-throughput sequencing library preparation, mammalian tissue culture, and FACS
Highly responsible, independent and interested in working with a multidisciplinary team and interacting with clinical trial teams
Knowledge of policies and protocols related to functioning of a research lab incl. lab safety
Master's degree with three years of wet-lab experience
Financial literacy and experience or ability to manage lab inventory and supplies preferred
Interest in adapting or developing new single-cell technologies for cancer research would be a plus
Previous experience with single-cell genomic technologies would be preferable
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 505512
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.