Research - Laboratory/Non-Laboratory, Staff/Administrative
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The Cancer Vaccine Institute is seeking an experienced scientist to lead our Immunologic Monitoring Core Laboratory. This person should be skilled in personnel management and act as an expert resource in immunologic assay execution for a multi-disciplinary group. The position will be responsible for reviewing research and recommending specific technology and methodology, designing technological phases of research projects and researching and developing new technology to meet the overall objectives of the Cancer Vaccine Institute. The position requires a strong regulatory background and experience in clinical assay execution and development. The scientist will develop hypotheses and draw conclusions based on expertise in technology used in research, perform basic data analysis, present research results at meetings and write methodological sections of grant proposals. The position will be responsible for direct, day-to-day supervision of research staff in the Immunologic Monitoring Core including making hiring decisions, employee performance reviews and disciplinary actions as needed. The position will be responsible for monitoring research staff skills, teaching new skills when needed, and developing laboratory skills orientation classes/seminars for incoming MD/Fellows on technologies used by the Cancer Vaccine Institute. This position will also oversee communications regarding sample handling and processing with external collaborators and clinical trial sites.
Duties include preparation and maintenance of laboratory reagents, chemicals, instruments and other equipment
Order reagents and keep track of laboratory supplies
Prepare PBMC or purified NK or T cell populations from whole blood
Cryopreservation and thawing of cells
Perform multiparameter flow cytometry and identify cytokine-producing T cells using intracellular staining
Perform cytokine ELISPOT assays
Stimulate and culture primary cells in vitro for up to several months
Conduct ELISA/Luminex assays to measure cytokine production
Perform lymphoproliferative assays and cytolytic killing assays
Record keeping, data collection and analysis
Interpret results and recommend modification of procedures as necessary
Present data in lab meetings as well as to external groups through the creation of reports, papers, and formal presentations
Read literature related to research projects
Create new plans to assist in the development of new protocols and procedures for testing immune responses
Perform validation of new assays
Contribute to writing of Standard Operating Procedures
Assist with library research and clerical work
Interact with and assist clinical personnel with logistical issues regarding collection and shipping of human samples to the lab
Communication and Teambuilding
Promote and contribute to the development of teamwork in the service and working relationships between the laboratory and other departments;
Form productive working relationships with co-workers. Communicate clearly, directly and on a timely basis;
Act as role model/mentor to new students and research technicians
Open to receiving feedback and making constructive changes as a result;
Open to receiving direction and asks for assistance when needed;
Demonstrate a courteous, respectful, professional attitude and behavior at all times.
Represent the group professionally
Quality Assessment and Improvement
Participate in and support quality assessment and improvement activities
Receptive to new ideas and procedures
Adapt to new routines and schedules as necessary
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Master's degree in immunology or related field acceptable plus a minimum of one year of experience as a laboratory manager
Knowledge of current immunology literature
Experience in cellular immunology and tissue culture, including preparation of PBMC, flow cytometry, and ELISPOT
Industry and/or clinical experience related to developing CLIA-certified procedures and methodologies strongly preferred
Excellent computer, organizational, and record keeping skills
Excellent written and oral communication skills; including ability to write and present data orally
Strong interpersonal skills, with the ability to work effectively within an established team environment
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
ASCP certification preferred
CONDITIONS OF EMPLOYMENT
The Cancer Vaccine Institute is located at the UW Medicine at South Lake Union campus in a translational research environment that includes laboratory, clinical research and administrative office areas. Work is typically deadline driven and requires a high level of accuracy, extensive communication with scientists, staff and external collaborators from diverse backgrounds. Work week occasionally exceeds 40 hours to complete projects or meet deadlines.
Must be flexible and able to work evenings, weekends and holidays as necessary
This position may be stressful at times in that there is a constant pressure for quick turnaround time on tests and quality control.
May be required to stand for periods of at least 2 hours at a time
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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