Research - Laboratory/Non-Laboratory, Staff/Administrative
The Translational NeuroEngineering Laboratory (TNEL) in the University of Minnesota Department of Psychiatry has a multi-year funded opening for a postdoctoral scholar at the intersection of neuroscience, brain stimulation, and behavior. Our laboratory develops technologies to reverse the circuit impairments that cause mental illness, including depression, obsessive-compulsive disorder, PTSD, and addictions. More information about our work is at http://www.tnelab.org/ .
The job duties (100%) in this project involve measuring and manipulating the activity of cortico-striatal circuits involved in complex decision-making, and specifically in governing the balance between flexible and rigid decision styles. Tools to be employed (and on which we can train you) include:
Novel silicon probes (Neuropixels) for recording hundreds of simultaneous channels across the striatal circuitry
Optogenetic and electrical real-time perturbations, including interventions directly related to clinical deep brain stimulation.
Innovative behavioral assays and parametric computational modeling of behavior to identify the underlying circuit computations.
The work has direct relevance to new treatments for obsessive-compulsive disorder, eating disorders, and depression, among other illnesses.
The majority of this position’s work will be with animals (rats), but we are a translational lab that also does human/clinical work, and you may be involved in preliminary human translation if that is of interest. Depending on your interests, there may also be opportunities/exposure to:
Medical device development and commercialization
Neural simulation and modeling paradigms
The clinical neurobiology of mental illness
Our goal is to prepare you to be successful in the future as an independent researcher. UMN has multiple training and seed grant programs to support that transition to independence. Our laboratory includes both animal and human research components, and you will interact almost daily with other neuroscientists and engineers. There are also opportunities for collaboration and networking with clinicians, basic neuroscientists, and engineers. We are very focused on mentoring and developing junior personnel, and the PI will work with you to ensure that you are submitting competitive applications for fellowships and other grants on the pathway to independence. We also have strong industry relations for researchers interested in careers outside academia.
We do have a staff scientist track for researchers interested in more long-term non-faculty positions; please indicate in your cover letter if that is where your interest lies.
This position is open to researchers of any nationality. We will happily sponsor a visa, but please tell us up front about your needs and current status.
We are similarly very interested in hearing from researchers from non-traditional or underrepresented backgrounds, and who may not have had all of the exposures/training mentioned above, but who are eager to learn and willing to work hard to master new skills. The UMN neuroscience community is committed to reversing historical inequities, and you will find a welcoming and supportive community here.
You must have:
A doctoral degree in a relevant field. "Relevant" is very broad. Scholars from neuroscience, biomedical engineering, psychology, physics, computer science, and many other disciplines have thrived in our team.
A strong command of and interest in decision science, evidenced by prior research in this general area.
Excellent verbal and written communication skills. Much of our work requires explaining complex technical concepts to non-domain-experts.
Substantial (and documented/proven) capability for independent work, problem-solving, and initiative-taking.
Interpersonal skills appropriate for collaboration in a very multidisciplinary and highly diverse environment.
It will be helpful (and we will give your application priority) if you have:
Prior experimental work in animal or human neuroscience, especially electrophysiology in any species
Any prior work in mathematical models of decision-making
Prior work with psychiatric patient populations or the biological mechanisms of mental illness
Skills with electronics or computer hardware, whether design or repair
Experience with brain-computer interfaces and/or brain decoding paradigms
Performing the job duties will require:
Standing or sitting for extended periods
Performing fine motor tasks under visual guidance
Independent analysis and interpretation of technical data
Complex technical communication in the English language
Professional interactions with a diverse body of colleagues and research participants
Acquisition and maintenance of all necessary requirements (e.g., background checks, immunizations, institutional trainings) for work with animal subjects, particularly outbred rats.
Internal Number: 338292
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.