Research - Laboratory/Non-Laboratory, Staff/Administrative
The Macklis Lab is directed toward (1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-circuit formation, and degeneration in the cerebral cortex, and (2) applying developmental controls toward brain and spinal cord regeneration and directed differentiation for in vitro therapeutic and mechanistic screening.
Under the supervision of the Principal Investigator and senior lab personnel, the laboratory technician will focus on one or more of the following areas:
molecular biology, including cloning and CRISPR gene editing;
mouse genetics, husbandry, behavior, neuroanatomy, and surgery;
cell culture, including directed differentiation of stem cells into neurons and brain organoids;
microscopy, tissue processing, CLARITY, and image analysis.
1. Perform standard tests and procedures, using developed approaches;
2. Under specific direction from senior lab personnel, maintain and genotype mouse lines and/or mammalian cell cultures;
3. Analyze experimental data, and troubleshoot experimental protocols to ensure successful and timely project completion.
4. Record experimental results and report data to supervisor and team.
5. Participate in weekly lab meetings and journal clubs.
6. Assist other staff and students in basic laboratory techniques including standard molecular biology techniques, cell culture techniques, microscopy, and/or animal care.
7. Perform related lab duties such as maintaining and cleaning equipment, preparing common stock solutions, monitoring supplies and communicate supply needs to lab manager.
8. Assist with the animal colony, including health and environmental conditions monitoring, breeding and recording of clinical observations.
This is a 1 year grant funded term position with the possibility of extension based on satisfactory performance and continued availability of funding.
All formal offers will be made by FAS Human Resources.
We invite individuals with diverse backgrounds, experiences and abilities to .be a part of our community
Salary Grade: 049
Union: 55 - Hvd Union Cler & Tech Workers
Experience with basic biological laboratory techniques is required.
BA/BS in biological sciences is preferred, as is directly related lab experience.
Excellent communication, organization, and time management skills.
High level of initiative and motivation; ability to work independently and with a team.
Attention to detail, especially in regard to executing experimental protocols.
Ability to think creatively to solve problems.
Interest in one or more of the following is preferred: nervous system development, gene editing technology, animal handling, surgical techniques, stem cell culture, and microscopy techniques
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 52870BR
About Harvard University Faculty of Arts and Sciences
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