Research - Laboratory/Non-Laboratory, Staff/Administrative
Preclinical Researcher Center
The Researcher 3 will perform high-quality structured procedures in a fast-paced research laboratory setting. This position will be a part of a team working to develop and support innovative therapies for diseases with major public health significance. This research focuses on cardiovascular, neurologic, metabolic (e.g. diabetes and obesity), and infectious disease (e.g. COVID19). They will develop study protocols, review results, compile reports and collect data according to standard operating procedures and regulations. They will be responsible for communicating with the PI and management all study subject and protocol related correspondence. Various animal and in vitro models complement or are required for our biomedical research, with a parallel research program at this center that is focused on improving welfare/quality of life of study subjects used and enhancing the translational value of these models. As such, the employee must have interest in cooperative handling, enrichment, and behavioral management with study subjects. They may occasionally assist in induction, surgical procedures and post-operative care. The translational and high regulatory research completed at PCRC requires attention to detail and the ability to follow precise written protocols. When not occupied with routine tasks, the employee is expected to participate in other lab tasks as assigned to advance the team’s work.
Salary will be commensurate with skills and experience.
Specific duties include:
Study Liaison – 50% - Independently collect physiological data according to study protocols, analyze samples - Sets up and operates laboratory equipment for collecting data, including basic equipment calibration and maintenance - Prepares records for planned study procedures for hard copy data collection. - Independently plan and execute in vitro work for complex study procedures. - Manage the implementation of studies and perform a variety of medical procedures according to study protocols (i.e sample preparation for analysis, handling cells). - Independently collect data related to procedures on detailed records, including recording of: study evaluations, procedures completed, supplies used, senior staff communications, budget, etc. by maintaining meticulous records and collection of data accurately in accordance with GLP guidelines. - Data management, including maintaining accurate reports, collecting and analyzing data sets for publication and final reports. - Critical disease model problem solving - Organizes data into tables and text utilizing Microsoft Excel and Word; engage with senior staff and PI to ensure accurate interpretation and recording of data; maintain study subject research chart. - Responsible for sensitive and confidential material. - Conducts research in accordance with GLP regulations, maintain regulatory files - Perform and assist with surgical induction and recovery of study subject if needed, as well as with laboratory/surgical procedures including but not limited to, in vitro cell models, tissue analysis, imaging, and surgery - Establish and maintain a working knowledge of the principles behind daily work. - Review enrollment criteria to determine study subjects eligibility. - Facilitate open and professional communication related to study subject and teamwork among a diverse team (researchers, students, DVMs, MDs)
Lab Technical Lead – 50% - Develops skills that are cross functional and uses time efficiently including helping other areas of the lab. - Find solutions to complex and routine technical or operational problems, typically resolving through standard operating procedures but will at times need to create novel solutions to complex problems. - Maintains a clean environment and ensures that areas are adequately ordered, stocked and that instruments and equipment are in good working order. - Calibrate equipment and be able to troubleshoot equipment properly - Initiate and revise lab SOPs as needed - Assemble instrument and packs as needed
- Develop protocols for process improvement projects. - Participate in lab meetings/rounds - Lead training and educational programs and tours - Must adhere to safety and infection control policies and procedures. - Review daily schedule, prioritize tasks to manage, coordinate, and alter order of work flow - Other duties as assigned by supervisor or Director
All required qualifications must be documented on application materials.
Requirements: - Bachelor’s degree in a natural science with at least two years of related experience in the animal sciences, biological sciences, biomedical engineering or related health sciences, or a master’s degree in a related field, or a combination of related education and experience to total six years. - Experience must include at least 2 years of direct experience with laboratory research, which may include but is not limited to in vitro cell culture techniques, and basic laboratory assays such as protein quantification, ELISA, and Western Blot - Experience with experimental recordkeeping, including reporting of experimental data, both raw and analyzed, and maintaining sample inventories - Experience with biological sample management, including handling of biological tissues and fluids and maintaining sample repository - Must be willing to work a flexible work week - Must be able to lift 50lbs by oneself, must be able to sit and stand for long periods - Must occasionally be available in the evenings for in vivo imaging studies - Desires a career that supports and promotes research - Must be able to wear appropriate personal protective equipment
Preferred: - Problem solving skills, strong interpersonal skills, attention to detail, and ability to work as a team member in a lab setting - Experience with conducting research according to scientific protocols, including reporting errors and summarizing data for reporting. - Experience managing and coordinating research subject’s involvement in research program - Experience with in vitro models for medical research, specifically preclinical based therapies. - Utilize the research process and standards to perform protocol-specific procedures, detail-oriented and willing to be accurate in all aspects of data collection - Experience with conducting research according to GLP regulations
Internal Number: 338133
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.