Research - Laboratory/Non-Laboratory, Research Support - Laboratory/Non-Laboratory, Staff/Administrative
The Research Assistant II position is responsible for assisting with research in genetics and diseases in marmoset models. Working as part of a multidisciplinary team, she/he will assist in the transgenesis of marmosets and the analysis of the phenotype of the marmoset model, including neuroimaging, behavioral tests, stereotaxic injection, tissue collection and sectioning, immunohistochemistry, PCR, DNA and RNA extractions and genotyping. We are looking for a motivated individual willing to learn colony maintenance such as pedigree recording and the techniques required in assisting transgenesis of marmosets, including reproductive hormone profiling, oocyte collection, in vitro fertilization and embryo transfer. Other responsibilities include data analysis and maintenance of tissue, DNA, and other experimental samples. Individuals will be expected to determine with moderate direction the timing of experiments, analysis, and presentation of results.
(70%) Transgenesis and Experimental Support for Marmoset Project
Significant focus on procedures in transgenesis of marmosets, including reproductive hormone profiling, monitoring animal health during surgery, embryo and oocyte collection, sperm collection, in vitro fertilization of oocytes and embryo transfer.
With moderate direction from senior staff, responsible for handling marmosets to address routine to moderately complex concerns; evaluates experimental and procedural criteria; makes recommendations for changes; and employs techniques for obtaining results.
Husbandry and maintenance of marmoset colonies and pedigree record keeping.
May learn and perform pedigree analysis and establish breeding based on analysis to maintain genetic diversity.
Performs animal monitoring under supervision of veterinary staff during surgery including but not limited to surgical preparation, anesthetic induction, animal monitoring, surgical assistance and post-operative recovery.
Assists with MRI/PET imaging, stereotaxic injections of viruses and other reagents, behavioral tests, peripheral injections, biopsies, perfusions, and necropsies.
Assists with marmoset requests and shipments, maintains animal inventory and attends staff meetings related to scope of work.
Prepares and presents experimental results at lab meetings.
(30%) Lab Maintenance
Assist technicians and post-docs with experiments as needed.
Stocks and organize incoming lab supplies as needed.
Attends staff meetings and assists with general problem solving.
Assists in writing of laboratory protocols for experiments.
Assists in Hazardous, Biohazardous, and Radioisotope waste disposal.
Assists in maintaining laboratory safety records.
Coordinates with vendors for problems regarding orders.
Minimum 2 years of related experience or equivalent combination of education and experience in a research environment.
Proficient in the operation of standard lab equipment and computer hardware/software.
Experience in veterinary or animal research support functions such as anesthesia and animal surgical support.
Bachelor's degree in biological sciences or related field or equivalent experience.
Registered veterinary technician license.
SKILLS AND ABILITIES
Demonstrated knowledge and experience in researching information and analyzing data to arrive at valid conclusions.
Ability to manage and track large numbers of samples meticulously without mix-up or cross contamination.
Skill in the operation and maintenance of various lab equipment.
Demonstrated knowledge and experience with both PC and MAC operating systems, standard business office equipment and commonly used software and tools, such as Microsoft Office, electronic mail, and the internet.
Proficiency with common office software applications as well as software applications used for research, recording, and analysis.
Highly organized, effective at multitasking, adept at juggling changing priorities and able to prioritize.
Proven ability to work both independently and also as part of a collaborative team.
Excellent communication skills, both oral and written.
Strong interpersonal skills, including tact, diplomacy, and flexibility.
Demonstrated ability to interact effectively with diverse groups. Demonstrated skill in establishing and maintaining effective working relationships with personnel at all levels.
Experience working with USDA (NHP preferred) covered species
Proficient with anesthesia (pre-per-post operative).
Experience in marmoset and mouse handling.
SPECIAL CONDITIONS OF EMPLOYMENT
Must be willing to work in an animal-related research environment.
Must be willing to work with human and non-human tissues and cells and complete all appropriate associated training.
Must be willing to work independently and must have a flexible schedule to support research needs.
Successful completion of the Institute’s background investigation.
Must be willing to sign a confidentiality agreement.
As a safeguard for employees and animals, this position may be subject to medical or safety clearance prior to working with specific animals or animal populations as required by research needs including but not limited to:
TB Testing/Clearance (every 12 months / once a year)
Measles (proof of immunity and/or adequate vaccination)
This position requires constant adjusting focus, seeing, sitting, and working inside.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
Salk scientists are dedicated to innovative biological research. The Salk Institute consistently ranks among the leading research institutions in the world for its faculty's contributions and the impact of their findings. Focused both on discovery and on mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes and infectious diseases by studying neuroscience, genetics, cell and plant biology, and related disciplines. "We lead biological research. We prize discovery. Salk is where cures begin."Overlooking the Pacific Ocean in La Jolla, the Salk Institute offers a warm, collegial and collaborative work environment, where employees enjoy a generous benefits program. Social activities on campus encourage interaction as a community.