Research - Laboratory/Non-Laboratory, Staff/Administrative
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Genome Sciences has an outstanding opportunity for a Research Scientist / Engineer 1.
This is an exciting opportunity for a Research Scientist/Engineer 1 (RSE1) to contribute to projects investigating the role of genomic structural variation in human disease and primate evolution, the genetic architecture of autism, and understanding natural genome variation between humans and other primates. The RSE1 will use cutting-edge techniques, including next-generation DNA sequencing, genomic clone characterization, and gene/protein characterization.
Actively contribute to the research results of the laboratory. Work collaboratively with other technicians; assist graduate students and postdoctoral fellows on multiple on-going research projects. Independently perform scientific investigative procedures.
•Library preparation, sequencer operation, data quality monitoring, and customer interaction duties. Support single-molecule, real-time (SMRT) sequencing projects on the Sequel II instrument associated with UW PacBio Sequencing Services. Full hands-on training provided, if necessary. •Select, prepare, sequence, assemble, and keep records of clones for PacBio sequencing. •Genotyping using PCR and qPCR. •Sample tracking and database maintenance. •DNA and RNA isolation from various sources. •Perform routine analysis of data using an interface and on the command line: assist with troubleshooting and daily quality control of data and assist researchers with data analysis, organization and interpretation, and experimental design. •Handle bacterial and human cell cultures, including clone picking, streaking agar plates, making stocks, and miniprep DNA isolation. •Perform related duties as required.
•Bachelor’s degree in Biology, Biochemistry, Microbiology or related Life Sciences field and two or more years related experience in a molecular biology, genomics, or biology laboratory. •Some exposure to next-generation sequencing and genomics laboratory techniques. •Able to work independently and as part of a multidisciplinary team. •Able to learn new techniques. •Attention to detail and strong organizational abilities. •Must have basic computing skills using Microsoft Word, Excel, and PowerPoint, or Google Docs and Sheets.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
•Master’s degree in Microbiology, Genetics or related Life Sciences field. •Experience and knowledge of the fundamental concepts, practices and procedures required for working in a genomics laboratory. •Knowledge of next-generation sequencing platforms and techniques. •PCR & qPCR for genotyping. •DNA & RNA isolation. •Some knowledge of sequence analysis, programs, and programming for bioinformatics. •Familiarity with human genomics terms and concepts. •Experience with UNIX/*NIX command line, BASH shell scripting, and Python.
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.
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