Research - Laboratory/Non-Laboratory, Staff/Administrative
This is a project-directed research position in a laboratory studying cell signaling, protein kinase regulation, myeloid-cell activation, autoimmune disease, and tumor-associated macrophages.
The successful candidate will work in a growing lab of an early-career principal investigator. They will receive significant mentoring from the principal investigator and help to interview, recruit, and train future labmates.
Close supervision will be provided initially, but it is expected that the successful candidate will eventually master their scientific field, contribute positively to the scientific culture of the laboratory, and present their own data and analysis in formal and informal settings. They will be motivated to ultimately generate important scientific results that will lead to publications in scientific journals.
70% Bench Research:
Assist in the design of research projects and perform the core experimental work of the lab, with guidance from the principal investigator. These tasks may involve, among other things, subcloning, cell culture, immunoblotting, and flow cytometry. Use critical thinking to thoroughly understand the goals and procedures necessary to complete assigned experiments. Independently troubleshoot issues that come up in experiments and use knowledge in molecular biology & immunology to support the direction and future aims of research projects assigned. Participate in regular lab meetings to report on data and explain scientific findings
25% Mouse Colony Maintenance:
Work with lab members to maintain optimal colony size, and work with veterinary staff and learn new protocols as necessary. Design/follow mating schema in order to breed desired mouse strains with correct genotypes. Ensure that investigator's lab is compliant with animal protocols. Keep detailed and careful documentation of any and all work that occurs in the mouse colony.
5% Lab Maintenance:
Manage the administrative duties related to the set up and efficient functioning of the lab. Share responsibility with other Researchers in the lab, preparing common reagents such as buffers and culture media.
All required qualifications must be documented on application materials
Bachelor's degree in the biological sciences or a combination of related education and work experience to equal four years.
Research experience in one or more of the following fields: cell signaling, immunology, autoimmunity, cancer biology, or biochemistry.
Good oral and written communication skills, a positive attitude, and a thoughtful approach to experimental design and troubleshooting.
Be able to work productively alone or as part of a team.
Scientific and personal integrity, strong work ethic, ability to learn new techniques, flexibility to change scientific or technical course, and enthusiasm for learning.
Willingness to work with mice
Desire to work at the interface of immune signaling, autoimmunity, and cancer biology
Willingness to perform some lab support tasks AND drive a research project
Undergraduate Research Experience: at least 12 months (e.g. two semesters and one summer OR three semesters).
Experience with Adobe Illustrator or Photoshop, Graphpad Prism, and/or Microsoft Office software
Project-based research experience, including semi-independent design of experiments, troubleshooting, writing a paper or giving a poster presentation, and mastering a scientific field by reading the literature and participating in group meetings
Research experience using one or more of the following methods: immunoblotting, flow cytometry, mouse models of cancer or autoimmunity, mouse breeding and handling, molecular cloning, mammalian cell culture with sterile technique, biochemical assays.
NOTE: FOR THE PURPOSES OF THE CV AND COVER LETTER, “EXPERIENCE WITH LAB METHODOLOGIES” MUST BE OBTAINED AS PART OF UNDERGRADUATE RESEARCH OR PAID LABORATORY EXPERIENCE, NOT SOLELY IN LABORATORY CLASSES.
Internal Number: 337700
About University of Minnesota, Twin Cities
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