The University of Kentucky Markey Cancer Center (MCC) is proud to be Kentucky's only National Cancer Institute-designated cancer center located in beautiful Lexington, Kentucky. The University of Kentucky is one of only a few universities in the country to have its undergraduate, medical and graduate colleges (16 total) and a nationally-recognized medical center and hospital on one central campus which allows for unique multidisciplinary collaborations. The MCC, consistently ranked in the top 50 cancer centers in the country by US News and World Report, is dedicated to driving a measurable reduction in cancer incidence and mortality in Kentucky through a comprehensive program of cancer research, prevention, community outreach, education and patient care.
We are currently recruiting a Scientist I to work within a team of talented multidisciplinary investigators on projects focused on the physiologic and pathophysiologic effects of the intestinal hormone neurotensin on obesity, fat metabolism, and mechanisms of obesity-associated cancers.
Key Responsibilities Include:
The newly hired Scientist I will work under the direction of the Principal Investigators and other senior laboratory personnel. The Scientist will lead their projects and also have the opportunity to interact and collaborate with the rich community of basic and translational scientists at the MCC. The research performed in the laboratory is focused on the intestinal hormone neurotensin (NT) and will extend novel findings published in Nature (Li, J et al. An obligatory role for neurotensin in high fat diet-induced obesity. Nature 533:411-415, 2016) identifying NT as an important contributor to obesity associated with consumption of a high fat diet. The newly hired Scientist will be involved in the following techniques and duties:
The Scientist will utilize multiple genetic mouse models, mouse and human intestinal organoid cultures, patient samples, Drosophila models, and other in vivo and in vitro model systems to identify the molecular mechanisms for fat deposition and fat metabolism associated with the increased release of NT.
The Scientist will further explore the biologic and clinical implications of NT on fat inflammation and as a potentially important link to obesity-associated cancers.
Finally, the successful candidate will be expected to write and submit manuscripts based on their findings and assist with grant applications.
Other highlights of the program include:
In addition to the research, the position will have a focus on career development including grant writing, scientific writing/presentation, mentorship of graduate students and technicians, networking, and building collaborations.
Qualifications, experience and skills required for consideration:
A Master's degree in life or biomedical sciences, or a related discipline is required;
The ability to drive an individual project with scientific rigor and also be highly collaborative with other academic partners;
The successful candidate should be highly self-motivated and organized, have a strong work ethic and desire to learn, and a proven track record of productivity;
Previous experience with mouse models, cancer biology, and cellular and molecular biology is highly desired.
Applicants must upload with application:
Cover letter discussing their interest in the position, research interests and long-term goals
As specific Request I, Contact information for three references
Excel, Photoshop, Word, Powerpoint, ability to analyze experimental results
Position Time Status: Full-Time
Required Related Experience:
No experience required.
Required License/Registration/Certification :
PhD in a biological science with 5 years of related experience
University Community of Inclusion:
The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus.
As an Equal Opportunity Employer, we strongly encourage veterans, individuals with disabilities, women, and all minorities to consider our employment opportunities.
Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.
Adjacent to downtown Lexington, UK is nestled in the scenic heart of the beautiful Bluegrass Region of Kentucky. UK's campus covers more than 814 acres, with more than 30,700 students and 13,500 full-time employees, including nearly 2,400 full-time faculty and librarians.