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Specialist – Okada Lab
Specialist – Okada Lab The assistant/associate/full specialist in this position is expected to conduct IND (investigational new drug)-enabling studies for our clinical trial of cancer immunotherapy for patients with glioma. Hence, the studies to be conducted include: 1) designing and cloning of novel lentiviral chimeric antigen receptor (CAR) vector; 2) transduction of human T lymphocytes with lentiviral CAR; 3) evaluation of anti-glioma immune responses by the CAR-transduced T lymphocytes using a variety of immunological assays, such as cytotoxicity assays, cytokine release assays and flow-cytometry; and 3) in vivo studies using immunodeficient mice bearing human glioma xenografts and infusion of CAR-transduced T lymphocytes. Sufficient expertise and knowledge in relevant
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