We focus on high throughput quantitative proteomics and disease-induced biomarkers studies at newly-founded Advanced Clinical BioSystems Research Institute (ACBRI) at Cedars-Sinai Medical Center Smidt Heart Institute. We perform experiments in cutting edge mass spectrometry applications in biomarker discoveries and validations. Our projects are on the development of and application of targeted protein quantification techniques for studying specific cellular pathways at the molecular level and for verification of protein candidate biomarkers for diagnosis, prognosis, and therapeutics from cells, tissues, and biofluids for heart diseases.
Under supervision of the Bioinformatics Lead, the Research Bioinformatician I (RBI) provides complex bioinformatics data analysis & software development support for projects involving omics data. The novel omics workflows being developed as part of the ongoing bioinformatics initiatives have fundamentally different analytical and visualization requirements. The incumbent will be responsible for implementing new software tools, maintaining existing in-house tools and perform data analysis.
Essential job duties and responsibilities:
Provides general bioinformatics analysis support for omics projects, assist in development, testing and maintenance of software pipelines for proteomics data analysis, statistical analysis, pathway analysis, and visualization.
Summarizes data analyses results in the form of visualization plots & reports to aid in preliminary interpretations of the data.
Software-engineering to improve usability, extensibility and scalability of existing programs including Development of custom software interfaces & automation/optimization/parallelization of tasks.
Helps to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literature in bioinformatics and computational biology.
Training & support for the scientists and technicians, maintaining the in-house tools and databases and supporting the bioinformatics team with their on-going efforts.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.