About the Job The Department of Obstetrics, Gynecology and Women’s Health is recruiting for a postoctoral fellow in the field of deubiquitinating enzymes and metabolic pathways regulating women's cancer initiation and progression.
The purpose of the work is to develop personalize therapies for ovarian cancer resistant to chemotherapy treatment and develop combinational chemotherapy treatment for ovarian cancer. Also understand the metabolic pathways for ovarian and cancer treatment. The responsibilities of this position will be to carry out research in the field of ovarian cancer. The research will include performing various molecular biology techniques, cell cultures as well as animal handling and experiments.
70% Carry out research investigations aimed at identifying causes and treatments for women's cancers. Duties include I) performing immunohistochemistry, immunofluorescence, quantitative PCR and western blot protein analysis; 2) investigation of mitochondrial dynamics in cancer cells, primary and cell lines. Live image microscopy visualizinf mitochondrial dynamics, movement and shape, 3) performing cell culture work including generation of stably transfected/transduced cell lines, and subsequent analysis of these cell lines using quantitative PCR, western blotting, cell proliferation assays, migration assays, and apoptosis assays, 4) preclinical work to test targeted chemotherapy
30%: Participate in the intellectual aspects of the project including literature review, critical analysis of published literature, critical analysis on own data, writing of manuscripts, revision of manuscripts, peer review of manuscripts, poster and oral presentation at national and international conferences.
- Post Doctoral - International Experience (Outside of the US) in the field of medical oncology - Published review on deubiquitinating enzymes in coronaviruses, which contains several therapeutic hypotheses for COVID19 - Previous experience working with UMN Faculty - This position requires a self-motivated individual capable of working independently on a number of different project. - This position requires proven experience to collect and analyze data and to write scientific peer-reviewed articles.
Ideally a candidate will have an MD degree They should have the ability to work with: - Cell cultures. - Microscopy - Biochemical techniques
Internal Number: 337554
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